Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then applied it to clinical samples for clinic...
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Nature Portfolio
2021
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oai:doaj.org-article:8d32c33c8ee2436bb93468943c33fa642021-12-02T17:26:55ZLabel-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device10.1038/s42003-021-02651-82399-3642https://doaj.org/article/8d32c33c8ee2436bb93468943c33fa642021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02651-8https://doaj.org/toc/2399-3642Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then applied it to clinical samples for clinically relevant mutation analyses.Jose Montoya MiraAjay A. SapreBrett S. WalkerJesus Bueno AlvarezKyle T. GustafsonEugene TuJared M. FischerMelissa H. WongSadik EsenerYu-Jui ChiuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021) |
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DOAJ |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Jose Montoya Mira Ajay A. Sapre Brett S. Walker Jesus Bueno Alvarez Kyle T. Gustafson Eugene Tu Jared M. Fischer Melissa H. Wong Sadik Esener Yu-Jui Chiu Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device |
description |
Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then applied it to clinical samples for clinically relevant mutation analyses. |
format |
article |
author |
Jose Montoya Mira Ajay A. Sapre Brett S. Walker Jesus Bueno Alvarez Kyle T. Gustafson Eugene Tu Jared M. Fischer Melissa H. Wong Sadik Esener Yu-Jui Chiu |
author_facet |
Jose Montoya Mira Ajay A. Sapre Brett S. Walker Jesus Bueno Alvarez Kyle T. Gustafson Eugene Tu Jared M. Fischer Melissa H. Wong Sadik Esener Yu-Jui Chiu |
author_sort |
Jose Montoya Mira |
title |
Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device |
title_short |
Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device |
title_full |
Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device |
title_fullStr |
Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device |
title_full_unstemmed |
Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device |
title_sort |
label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/8d32c33c8ee2436bb93468943c33fa64 |
work_keys_str_mv |
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