Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device

Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then applied it to clinical samples for clinic...

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Autores principales: Jose Montoya Mira, Ajay A. Sapre, Brett S. Walker, Jesus Bueno Alvarez, Kyle T. Gustafson, Eugene Tu, Jared M. Fischer, Melissa H. Wong, Sadik Esener, Yu-Jui Chiu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8d32c33c8ee2436bb93468943c33fa64
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spelling oai:doaj.org-article:8d32c33c8ee2436bb93468943c33fa642021-12-02T17:26:55ZLabel-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device10.1038/s42003-021-02651-82399-3642https://doaj.org/article/8d32c33c8ee2436bb93468943c33fa642021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02651-8https://doaj.org/toc/2399-3642Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then applied it to clinical samples for clinically relevant mutation analyses.Jose Montoya MiraAjay A. SapreBrett S. WalkerJesus Bueno AlvarezKyle T. GustafsonEugene TuJared M. FischerMelissa H. WongSadik EsenerYu-Jui ChiuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Jose Montoya Mira
Ajay A. Sapre
Brett S. Walker
Jesus Bueno Alvarez
Kyle T. Gustafson
Eugene Tu
Jared M. Fischer
Melissa H. Wong
Sadik Esener
Yu-Jui Chiu
Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
description Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then applied it to clinical samples for clinically relevant mutation analyses.
format article
author Jose Montoya Mira
Ajay A. Sapre
Brett S. Walker
Jesus Bueno Alvarez
Kyle T. Gustafson
Eugene Tu
Jared M. Fischer
Melissa H. Wong
Sadik Esener
Yu-Jui Chiu
author_facet Jose Montoya Mira
Ajay A. Sapre
Brett S. Walker
Jesus Bueno Alvarez
Kyle T. Gustafson
Eugene Tu
Jared M. Fischer
Melissa H. Wong
Sadik Esener
Yu-Jui Chiu
author_sort Jose Montoya Mira
title Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
title_short Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
title_full Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
title_fullStr Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
title_full_unstemmed Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
title_sort label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8d32c33c8ee2436bb93468943c33fa64
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