A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA
Replication Protein A (RPA) coats single stranded DNA (ssDNA) generated during DNA recombination, replication and repair. Here the authors present a structural model suggesting how RPA’s DNA-binding domains promote cooperative assembly of multiple RPAs on long ssDNA.
Guardado en:
Autores principales: | Luke A. Yates, Ricardo J. Aramayo, Nilisha Pokhrel, Colleen C. Caldwell, Joshua A. Kaplan, Rajika L. Perera, Maria Spies, Edwin Antony, Xiaodong Zhang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8d342a9ef98841d4b568cbf8c3f546c6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
por: Zhi-Xiong Zhou, et al.
Publicado: (2019) -
Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
por: Marta A. Garbacz, et al.
Publicado: (2018) -
Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks.
por: Bing Xu, et al.
Publicado: (2011) -
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks
por: Ann-Marie K. Shorrocks, et al.
Publicado: (2021) -
Analysis of replication intermediates indicates that Drosophila melanogaster mitochondrial DNA replicates by a strand-coupled theta mechanism.
por: Priit Jõers, et al.
Publicado: (2013)