Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT

Abstract Local field potentials (LFP) have been the focus of many recent studies in systems neuroscience. However, the exact neural basis of these signals remains unclear. To address this question, we determined the relationship between LFP signals and another, much better understood, signature of n...

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Autores principales:	Moein Esghaei, Mohammad Reza Daliri, Stefan Treue
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8d38288196444a65a3da1095e2d1da76
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spelling	oai:doaj.org-article:8d38288196444a65a3da1095e2d1da762021-12-02T15:05:11ZLocal field potentials are induced by visually evoked spiking activity in macaque cortical area MT10.1038/s41598-017-17372-42045-2322https://doaj.org/article/8d38288196444a65a3da1095e2d1da762017-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-17372-4https://doaj.org/toc/2045-2322Abstract Local field potentials (LFP) have been the focus of many recent studies in systems neuroscience. However, the exact neural basis of these signals remains unclear. To address this question, we determined the relationship between LFP signals and another, much better understood, signature of neural activity: action potentials. Specifically, we focused on the relationship between the amplitude of stimulus-induced LFPs and the magnitude of spiking activity in visual cortex of non-human primates. Our trial-by-trial correlation analyses between these two components of extracellular signals in macaque visual cortex show that the spike rate is coupled to the LFP amplitude with a surprisingly long latency, typically 50 ms. Our analysis shows that the neural spike rate is a significant predictor of the LFP amplitude. This limits the functional interpretation of LFP signals beyond that based on spiking activities.Moein EsghaeiMohammad Reza DaliriStefan TreueNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Moein Esghaei Mohammad Reza Daliri Stefan Treue Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT
description	Abstract Local field potentials (LFP) have been the focus of many recent studies in systems neuroscience. However, the exact neural basis of these signals remains unclear. To address this question, we determined the relationship between LFP signals and another, much better understood, signature of neural activity: action potentials. Specifically, we focused on the relationship between the amplitude of stimulus-induced LFPs and the magnitude of spiking activity in visual cortex of non-human primates. Our trial-by-trial correlation analyses between these two components of extracellular signals in macaque visual cortex show that the spike rate is coupled to the LFP amplitude with a surprisingly long latency, typically 50 ms. Our analysis shows that the neural spike rate is a significant predictor of the LFP amplitude. This limits the functional interpretation of LFP signals beyond that based on spiking activities.
format	article
author	Moein Esghaei Mohammad Reza Daliri Stefan Treue
author_facet	Moein Esghaei Mohammad Reza Daliri Stefan Treue
author_sort	Moein Esghaei
title	Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT
title_short	Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT
title_full	Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT
title_fullStr	Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT
title_full_unstemmed	Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT
title_sort	local field potentials are induced by visually evoked spiking activity in macaque cortical area mt
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8d38288196444a65a3da1095e2d1da76
work_keys_str_mv	AT moeinesghaei localfieldpotentialsareinducedbyvisuallyevokedspikingactivityinmacaquecorticalareamt AT mohammadrezadaliri localfieldpotentialsareinducedbyvisuallyevokedspikingactivityinmacaquecorticalareamt AT stefantreue localfieldpotentialsareinducedbyvisuallyevokedspikingactivityinmacaquecorticalareamt
_version_	1718388904442200064

Local field potentials are induced by visually evoked spiking activity in macaque cortical area MT

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