CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens

CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens

Sparse immune-binding data for emerging pathogens limits the ability of existing in silico antigenicity prediction methods to aid vaccine design. Here, the authors introduce a computational method that estimates antigenic pathogen similarity based on epitope structure.

Guardado en:
Detalles Bibliográficos
Autores principales: Tianyi Qiu, Yiyan Yang, Jingxuan Qiu, Yang Huang, Tianlei Xu, Han Xiao, Dingfeng Wu, Qingchen Zhang, Chen Zhou, Xiaoyan Zhang, Kailin Tang, Jianqing Xu, Zhiwei Cao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/8d39d46958ac4c429656ad5840831e53
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:8d39d46958ac4c429656ad5840831e53
record_format dspace
spelling oai:doaj.org-article:8d39d46958ac4c429656ad5840831e532021-12-02T15:34:36ZCE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens10.1038/s41467-018-04171-22041-1723https://doaj.org/article/8d39d46958ac4c429656ad5840831e532018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04171-2https://doaj.org/toc/2041-1723Sparse immune-binding data for emerging pathogens limits the ability of existing in silico antigenicity prediction methods to aid vaccine design. Here, the authors introduce a computational method that estimates antigenic pathogen similarity based on epitope structure.Tianyi QiuYiyan YangJingxuan QiuYang HuangTianlei XuHan XiaoDingfeng WuQingchen ZhangChen ZhouXiaoyan ZhangKailin TangJianqing XuZhiwei CaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tianyi Qiu
Yiyan Yang
Jingxuan Qiu
Yang Huang
Tianlei Xu
Han Xiao
Dingfeng Wu
Qingchen Zhang
Chen Zhou
Xiaoyan Zhang
Kailin Tang
Jianqing Xu
Zhiwei Cao
CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens
description Sparse immune-binding data for emerging pathogens limits the ability of existing in silico antigenicity prediction methods to aid vaccine design. Here, the authors introduce a computational method that estimates antigenic pathogen similarity based on epitope structure.
format article
author Tianyi Qiu
Yiyan Yang
Jingxuan Qiu
Yang Huang
Tianlei Xu
Han Xiao
Dingfeng Wu
Qingchen Zhang
Chen Zhou
Xiaoyan Zhang
Kailin Tang
Jianqing Xu
Zhiwei Cao
author_facet Tianyi Qiu
Yiyan Yang
Jingxuan Qiu
Yang Huang
Tianlei Xu
Han Xiao
Dingfeng Wu
Qingchen Zhang
Chen Zhou
Xiaoyan Zhang
Kailin Tang
Jianqing Xu
Zhiwei Cao
author_sort Tianyi Qiu
title CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens
title_short CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens
title_full CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens
title_fullStr CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens
title_full_unstemmed CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens
title_sort ce-blast makes it possible to compute antigenic similarity for newly emerging pathogens
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/8d39d46958ac4c429656ad5840831e53
work_keys_str_mv AT tianyiqiu ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT yiyanyang ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT jingxuanqiu ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT yanghuang ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT tianleixu ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT hanxiao ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT dingfengwu ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT qingchenzhang ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT chenzhou ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT xiaoyanzhang ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT kailintang ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT jianqingxu ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
AT zhiweicao ceblastmakesitpossibletocomputeantigenicsimilarityfornewlyemergingpathogens
_version_ 1718386792062779392

Ejemplares similares