Finding gene network topologies for given biological function with recurrent neural network

Networks are useful ways to describe interactions between molecules in a cell, but predicting the real topology of large networks can be challenging. Here, the authors use deep learning to predict the topology of networks that perform biologically-plausible functions.

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Auteurs principaux: Jingxiang Shen, Feng Liu, Yuhai Tu, Chao Tang
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/8d4a9caf655a48a7a4ae61cbbeee9d44
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spelling oai:doaj.org-article:8d4a9caf655a48a7a4ae61cbbeee9d442021-12-02T16:52:57ZFinding gene network topologies for given biological function with recurrent neural network10.1038/s41467-021-23420-52041-1723https://doaj.org/article/8d4a9caf655a48a7a4ae61cbbeee9d442021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23420-5https://doaj.org/toc/2041-1723Networks are useful ways to describe interactions between molecules in a cell, but predicting the real topology of large networks can be challenging. Here, the authors use deep learning to predict the topology of networks that perform biologically-plausible functions.Jingxiang ShenFeng LiuYuhai TuChao TangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jingxiang Shen
Feng Liu
Yuhai Tu
Chao Tang
Finding gene network topologies for given biological function with recurrent neural network
description Networks are useful ways to describe interactions between molecules in a cell, but predicting the real topology of large networks can be challenging. Here, the authors use deep learning to predict the topology of networks that perform biologically-plausible functions.
format article
author Jingxiang Shen
Feng Liu
Yuhai Tu
Chao Tang
author_facet Jingxiang Shen
Feng Liu
Yuhai Tu
Chao Tang
author_sort Jingxiang Shen
title Finding gene network topologies for given biological function with recurrent neural network
title_short Finding gene network topologies for given biological function with recurrent neural network
title_full Finding gene network topologies for given biological function with recurrent neural network
title_fullStr Finding gene network topologies for given biological function with recurrent neural network
title_full_unstemmed Finding gene network topologies for given biological function with recurrent neural network
title_sort finding gene network topologies for given biological function with recurrent neural network
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8d4a9caf655a48a7a4ae61cbbeee9d44
work_keys_str_mv AT jingxiangshen findinggenenetworktopologiesforgivenbiologicalfunctionwithrecurrentneuralnetwork
AT fengliu findinggenenetworktopologiesforgivenbiologicalfunctionwithrecurrentneuralnetwork
AT yuhaitu findinggenenetworktopologiesforgivenbiologicalfunctionwithrecurrentneuralnetwork
AT chaotang findinggenenetworktopologiesforgivenbiologicalfunctionwithrecurrentneuralnetwork
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