Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men

Abstract The role that serum uric acid (UA) plays in the pathophysiological development of erectile dysfunction (ED) is controversial. We aimed to screen the factors related with ED, and to examine the association between serum UA and ED. Our data were derived from a cross-sectional Survey on Preval...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Fengbin Gao, Boren Jiang, Zhen Cang, Ningjian Wang, Bing Han, Qin Li, Yi Chen, Yingchao Chen, Fangzhen Xia, Hualing Zhai, Chi Chen, Meng Lu, Ying Meng, Yingli Lu, Zhoujun Shen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8d4ac69e2d54489fb085117c547f7bbc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8d4ac69e2d54489fb085117c547f7bbc
record_format	dspace
spelling	oai:doaj.org-article:8d4ac69e2d54489fb085117c547f7bbc2021-12-02T11:52:27ZSerum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men10.1038/s41598-017-02392-x2045-2322https://doaj.org/article/8d4ac69e2d54489fb085117c547f7bbc2017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-02392-xhttps://doaj.org/toc/2045-2322Abstract The role that serum uric acid (UA) plays in the pathophysiological development of erectile dysfunction (ED) is controversial. We aimed to screen the factors related with ED, and to examine the association between serum UA and ED. Our data were derived from a cross-sectional Survey on Prevalence in East China for Metabolic Diseases and Risk Factors study in 2014–2015. Questionnaire of International Index of Erectile Dysfunction-5 was used for assessment of ED. Data were collected in three general communities respectively. A total of 1365 men were enrolled with an overall mean age 55.5 ± 10.8 years (range: 20–83 years). The prevalence of ED was 62.4% (51.4% standardized) in the population. Males with ED were older, and more prone to have a higher follicle-stimulating hormone, luteinizing hormone, sex hormone-binding globulin, glycated hemoglobin, fasting plasma glucose levels and lower free androgen index (FAI), UA levels, and more likely to have diabetes and elevated blood pressure compared with those without ED. Age and UA were independent influencing factors for ED. Besides, UA was positively correlated with FAI after adjustment for age. In conclusion, our study demonstrated the protective role that UA might play in development of ED.Fengbin GaoBoren JiangZhen CangNingjian WangBing HanQin LiYi ChenYingchao ChenFangzhen XiaHualing ZhaiChi ChenMeng LuYing MengYingli LuZhoujun ShenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Fengbin Gao Boren Jiang Zhen Cang Ningjian Wang Bing Han Qin Li Yi Chen Yingchao Chen Fangzhen Xia Hualing Zhai Chi Chen Meng Lu Ying Meng Yingli Lu Zhoujun Shen Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
description	Abstract The role that serum uric acid (UA) plays in the pathophysiological development of erectile dysfunction (ED) is controversial. We aimed to screen the factors related with ED, and to examine the association between serum UA and ED. Our data were derived from a cross-sectional Survey on Prevalence in East China for Metabolic Diseases and Risk Factors study in 2014–2015. Questionnaire of International Index of Erectile Dysfunction-5 was used for assessment of ED. Data were collected in three general communities respectively. A total of 1365 men were enrolled with an overall mean age 55.5 ± 10.8 years (range: 20–83 years). The prevalence of ED was 62.4% (51.4% standardized) in the population. Males with ED were older, and more prone to have a higher follicle-stimulating hormone, luteinizing hormone, sex hormone-binding globulin, glycated hemoglobin, fasting plasma glucose levels and lower free androgen index (FAI), UA levels, and more likely to have diabetes and elevated blood pressure compared with those without ED. Age and UA were independent influencing factors for ED. Besides, UA was positively correlated with FAI after adjustment for age. In conclusion, our study demonstrated the protective role that UA might play in development of ED.
format	article
author	Fengbin Gao Boren Jiang Zhen Cang Ningjian Wang Bing Han Qin Li Yi Chen Yingchao Chen Fangzhen Xia Hualing Zhai Chi Chen Meng Lu Ying Meng Yingli Lu Zhoujun Shen
author_facet	Fengbin Gao Boren Jiang Zhen Cang Ningjian Wang Bing Han Qin Li Yi Chen Yingchao Chen Fangzhen Xia Hualing Zhai Chi Chen Meng Lu Ying Meng Yingli Lu Zhoujun Shen
author_sort	Fengbin Gao
title	Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
title_short	Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
title_full	Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
title_fullStr	Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
title_full_unstemmed	Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
title_sort	serum uric acid is associated with erectile dysfunction: a population-based cross-sectional study in chinese men
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8d4ac69e2d54489fb085117c547f7bbc
work_keys_str_mv	AT fengbingao serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT borenjiang serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT zhencang serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT ningjianwang serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT binghan serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT qinli serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT yichen serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT yingchaochen serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT fangzhenxia serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT hualingzhai serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT chichen serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT menglu serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT yingmeng serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT yinglilu serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen AT zhoujunshen serumuricacidisassociatedwitherectiledysfunctionapopulationbasedcrosssectionalstudyinchinesemen
_version_	1718395057361387520

Serum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men

Ejemplares similares