Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool

Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool

Nibu Parameswaran Nair, Leanne Chalmers, Gregory M Peterson, Bonnie J Bereznicki, Ronald L Castelino, Luke R Bereznicki Division of Pharmacy, School of Medicine, Faculty of Health, University of Tasmania, Hobart, TAS, Australia Abstract: Adverse drug reactions (ADRs) represent a major burden on so...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Parameswaran Nair N, Chalmers L, Peterson GM, Bereznicki BJ, Castelino RL, Bereznicki LR
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
Materias:
adverse drug reactions
hospital admission
prediction
older patients
Geriatrics
RC952-954.6
Acceso en línea:https://doaj.org/article/8d57c94471a9446e9be0103f181c06f9
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:8d57c94471a9446e9be0103f181c06f9
record_format dspace
spelling oai:doaj.org-article:8d57c94471a9446e9be0103f181c06f92021-12-02T06:51:17ZHospitalization in older patients due to adverse drug reactions – the need for a prediction tool1178-1998https://doaj.org/article/8d57c94471a9446e9be0103f181c06f92016-05-01T00:00:00Zhttps://www.dovepress.com/hospitalization-in-older-patients-due-to-adverse-drug-reactions-acirc--peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Nibu Parameswaran Nair, Leanne Chalmers, Gregory M Peterson, Bonnie J Bereznicki, Ronald L Castelino, Luke R Bereznicki Division of Pharmacy, School of Medicine, Faculty of Health, University of Tasmania, Hobart, TAS, Australia Abstract: Adverse drug reactions (ADRs) represent a major burden on society, resulting in significant morbidity, mortality, and health care costs. Older patients living in the community are particularly susceptible to ADRs, and are at an increased risk of ADR-related hospitalization. This review summarizes the available evidence on ADR-related hospital admission in older patients living in the community, with a particular focus on risk factors for ADRs leading to hospital admission and the need for a prediction tool for risk of ADR-related hospitalization in these individuals. The reported proportion of hospital admissions due to ADRs has ranged from 6% to 12% of all admissions in older patients. The main risk factors or predictors for ADR-related admissions were advanced age, polypharmacy, comorbidity, and potentially inappropriate medications. There is a clear need to design intervention strategies to prevent ADR-related hospitalization in older patients. To ensure the cost-effectiveness of such strategies, it would be necessary to target them to those older individuals who are at highest risk of ADR-related hospitalization. Currently, there are no validated tools to assess the risk of ADRs in primary care. There is a clear need to investigate the utility of tools to identify high-risk patients to target appropriate interventions toward prevention of ADR-related hospital admissions. Keywords: adverse drug reactions, hospital admission, prediction, older patients, primary care, risk factorsParameswaran Nair NChalmers LPeterson GMBereznicki BJCastelino RLBereznicki LRDove Medical Pressarticleadverse drug reactionshospital admissionpredictionolder patientsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 11, Pp 497-505 (2016)
institution DOAJ
collection DOAJ
language EN
topic adverse drug reactions
hospital admission
prediction
older patients
Geriatrics
RC952-954.6
spellingShingle adverse drug reactions
hospital admission
prediction
older patients
Geriatrics
RC952-954.6
Parameswaran Nair N
Chalmers L
Peterson GM
Bereznicki BJ
Castelino RL
Bereznicki LR
Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool
description Nibu Parameswaran Nair, Leanne Chalmers, Gregory M Peterson, Bonnie J Bereznicki, Ronald L Castelino, Luke R Bereznicki Division of Pharmacy, School of Medicine, Faculty of Health, University of Tasmania, Hobart, TAS, Australia Abstract: Adverse drug reactions (ADRs) represent a major burden on society, resulting in significant morbidity, mortality, and health care costs. Older patients living in the community are particularly susceptible to ADRs, and are at an increased risk of ADR-related hospitalization. This review summarizes the available evidence on ADR-related hospital admission in older patients living in the community, with a particular focus on risk factors for ADRs leading to hospital admission and the need for a prediction tool for risk of ADR-related hospitalization in these individuals. The reported proportion of hospital admissions due to ADRs has ranged from 6% to 12% of all admissions in older patients. The main risk factors or predictors for ADR-related admissions were advanced age, polypharmacy, comorbidity, and potentially inappropriate medications. There is a clear need to design intervention strategies to prevent ADR-related hospitalization in older patients. To ensure the cost-effectiveness of such strategies, it would be necessary to target them to those older individuals who are at highest risk of ADR-related hospitalization. Currently, there are no validated tools to assess the risk of ADRs in primary care. There is a clear need to investigate the utility of tools to identify high-risk patients to target appropriate interventions toward prevention of ADR-related hospital admissions. Keywords: adverse drug reactions, hospital admission, prediction, older patients, primary care, risk factors
format article
author Parameswaran Nair N
Chalmers L
Peterson GM
Bereznicki BJ
Castelino RL
Bereznicki LR
author_facet Parameswaran Nair N
Chalmers L
Peterson GM
Bereznicki BJ
Castelino RL
Bereznicki LR
author_sort Parameswaran Nair N
title Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool
title_short Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool
title_full Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool
title_fullStr Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool
title_full_unstemmed Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool
title_sort hospitalization in older patients due to adverse drug reactions – the need for a prediction tool
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/8d57c94471a9446e9be0103f181c06f9
work_keys_str_mv AT parameswarannairn hospitalizationinolderpatientsduetoadversedrugreactionsnbspndashtheneedforapredictiontool
AT chalmersl hospitalizationinolderpatientsduetoadversedrugreactionsnbspndashtheneedforapredictiontool
AT petersongm hospitalizationinolderpatientsduetoadversedrugreactionsnbspndashtheneedforapredictiontool
AT bereznickibj hospitalizationinolderpatientsduetoadversedrugreactionsnbspndashtheneedforapredictiontool
AT castelinorl hospitalizationinolderpatientsduetoadversedrugreactionsnbspndashtheneedforapredictiontool
AT bereznickilr hospitalizationinolderpatientsduetoadversedrugreactionsnbspndashtheneedforapredictiontool
_version_ 1718399705083281408

Ejemplares similares