Modeling early stage atherosclerosis in a primary human vascular microphysiological system

Human microphysiological systems (MPS) have some advantages over animal models to study the mechanisms of disease. Here the authors use a tissue-engineered blood vessel MPS to create a model of early stage atherosclerosis and assess the effect of several drugs.

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Autores principales:	Xu Zhang, Muath Bishawi, Ge Zhang, Varun Prasad, Ellen Salmon, Jason J. Breithaupt, Qiao Zhang, George A. Truskey
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8d57cac5f23b4a1ca7ed71c83c025052
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spelling	oai:doaj.org-article:8d57cac5f23b4a1ca7ed71c83c0250522021-12-02T17:32:12ZModeling early stage atherosclerosis in a primary human vascular microphysiological system10.1038/s41467-020-19197-82041-1723https://doaj.org/article/8d57cac5f23b4a1ca7ed71c83c0250522020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19197-8https://doaj.org/toc/2041-1723Human microphysiological systems (MPS) have some advantages over animal models to study the mechanisms of disease. Here the authors use a tissue-engineered blood vessel MPS to create a model of early stage atherosclerosis and assess the effect of several drugs.Xu ZhangMuath BishawiGe ZhangVarun PrasadEllen SalmonJason J. BreithauptQiao ZhangGeorge A. TruskeyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xu Zhang Muath Bishawi Ge Zhang Varun Prasad Ellen Salmon Jason J. Breithaupt Qiao Zhang George A. Truskey Modeling early stage atherosclerosis in a primary human vascular microphysiological system
description	Human microphysiological systems (MPS) have some advantages over animal models to study the mechanisms of disease. Here the authors use a tissue-engineered blood vessel MPS to create a model of early stage atherosclerosis and assess the effect of several drugs.
format	article
author	Xu Zhang Muath Bishawi Ge Zhang Varun Prasad Ellen Salmon Jason J. Breithaupt Qiao Zhang George A. Truskey
author_facet	Xu Zhang Muath Bishawi Ge Zhang Varun Prasad Ellen Salmon Jason J. Breithaupt Qiao Zhang George A. Truskey
author_sort	Xu Zhang
title	Modeling early stage atherosclerosis in a primary human vascular microphysiological system
title_short	Modeling early stage atherosclerosis in a primary human vascular microphysiological system
title_full	Modeling early stage atherosclerosis in a primary human vascular microphysiological system
title_fullStr	Modeling early stage atherosclerosis in a primary human vascular microphysiological system
title_full_unstemmed	Modeling early stage atherosclerosis in a primary human vascular microphysiological system
title_sort	modeling early stage atherosclerosis in a primary human vascular microphysiological system
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8d57cac5f23b4a1ca7ed71c83c025052
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Modeling early stage atherosclerosis in a primary human vascular microphysiological system

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