A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation

In teaching biology, it is critical to communicate broad concepts before considering more specific details of a process. This is particularly important when attempting to communicate the essence of transpeptidation, a key process in translation. Based on my experience in teaching general microbiolog...

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Autor principal:	Donald A. Klein
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2010
Materias:	Special aspects of education LC8-6691 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/8d57caf8f7a94cf7b278d47931cd1135
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spelling	oai:doaj.org-article:8d57caf8f7a94cf7b278d47931cd11352021-11-15T15:04:11ZA Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation10.1128/jmbe.v11i2.2071935-78851935-7877https://doaj.org/article/8d57caf8f7a94cf7b278d47931cd11352010-01-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/jmbe.v11i2.207https://doaj.org/toc/1935-7877https://doaj.org/toc/1935-7885In teaching biology, it is critical to communicate broad concepts before considering more specific details of a process. This is particularly important when attempting to communicate the essence of transpeptidation, a key process in translation. Based on my experience in teaching general microbiology, transpeptidation is the most difficult aspect of translation for students to understand. Typically, figures given in microbiology and biochemistry texts show movement of the nascent peptide attached to the P position t-RNA to the incoming single amino acid attached to the A position amino acid-tRNA by the use of arrows, an approach that makes it difficult to understand the dynamic aspects of this process. To attempt to improve understanding of this process, tutorials also are available that emphasize decoding “messages” and the use of “Do-it-Yourself DNA Kits” where the process of transpeptidation is not specifically discussed. The simple model described in this communication provides a clear demonstration of the transpeptidation process.Donald A. KleinAmerican Society for MicrobiologyarticleSpecial aspects of educationLC8-6691Biology (General)QH301-705.5ENJournal of Microbiology & Biology Education, Vol 11, Iss 2, Pp 172-174 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Special aspects of education LC8-6691 Biology (General) QH301-705.5
spellingShingle	Special aspects of education LC8-6691 Biology (General) QH301-705.5 Donald A. Klein A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation
description	In teaching biology, it is critical to communicate broad concepts before considering more specific details of a process. This is particularly important when attempting to communicate the essence of transpeptidation, a key process in translation. Based on my experience in teaching general microbiology, transpeptidation is the most difficult aspect of translation for students to understand. Typically, figures given in microbiology and biochemistry texts show movement of the nascent peptide attached to the P position t-RNA to the incoming single amino acid attached to the A position amino acid-tRNA by the use of arrows, an approach that makes it difficult to understand the dynamic aspects of this process. To attempt to improve understanding of this process, tutorials also are available that emphasize decoding “messages” and the use of “Do-it-Yourself DNA Kits” where the process of transpeptidation is not specifically discussed. The simple model described in this communication provides a clear demonstration of the transpeptidation process.
format	article
author	Donald A. Klein
author_facet	Donald A. Klein
author_sort	Donald A. Klein
title	A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation
title_short	A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation
title_full	A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation
title_fullStr	A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation
title_full_unstemmed	A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation
title_sort	simple wooden ribosome model: helping students understand transpeptidation
publisher	American Society for Microbiology
publishDate	2010
url	https://doaj.org/article/8d57caf8f7a94cf7b278d47931cd1135
work_keys_str_mv	AT donaldaklein asimplewoodenribosomemodelhelpingstudentsunderstandtranspeptidation AT donaldaklein simplewoodenribosomemodelhelpingstudentsunderstandtranspeptidation
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A Simple Wooden Ribosome Model: Helping Students Understand Transpeptidation

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