An experimental phylogeny to benchmark ancestral sequence reconstruction

Methods for ancestral sequence reconstruction are currently tested with computer simulations, since true biological phylogenies are unknown. Here, Randall et al.build an experimental phylogeny to benchmark the performance of alternate ancestral sequence reconstruction algorithms in inferring ancestr...

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Autores principales: Ryan N. Randall, Caelan E. Radford, Kelsey A. Roof, Divya K. Natarajan, Eric A. Gaucher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8d76cf698a8e469bb081b9dabe390bf7
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Sumario:Methods for ancestral sequence reconstruction are currently tested with computer simulations, since true biological phylogenies are unknown. Here, Randall et al.build an experimental phylogeny to benchmark the performance of alternate ancestral sequence reconstruction algorithms in inferring ancestral genotypes and phenotypes.