An experimental phylogeny to benchmark ancestral sequence reconstruction

Methods for ancestral sequence reconstruction are currently tested with computer simulations, since true biological phylogenies are unknown. Here, Randall et al.build an experimental phylogeny to benchmark the performance of alternate ancestral sequence reconstruction algorithms in inferring ancestr...

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Autores principales: Ryan N. Randall, Caelan E. Radford, Kelsey A. Roof, Divya K. Natarajan, Eric A. Gaucher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8d76cf698a8e469bb081b9dabe390bf7
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spelling oai:doaj.org-article:8d76cf698a8e469bb081b9dabe390bf72021-12-02T14:38:56ZAn experimental phylogeny to benchmark ancestral sequence reconstruction10.1038/ncomms128472041-1723https://doaj.org/article/8d76cf698a8e469bb081b9dabe390bf72016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12847https://doaj.org/toc/2041-1723Methods for ancestral sequence reconstruction are currently tested with computer simulations, since true biological phylogenies are unknown. Here, Randall et al.build an experimental phylogeny to benchmark the performance of alternate ancestral sequence reconstruction algorithms in inferring ancestral genotypes and phenotypes.Ryan N. RandallCaelan E. RadfordKelsey A. RoofDivya K. NatarajanEric A. GaucherNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-6 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ryan N. Randall
Caelan E. Radford
Kelsey A. Roof
Divya K. Natarajan
Eric A. Gaucher
An experimental phylogeny to benchmark ancestral sequence reconstruction
description Methods for ancestral sequence reconstruction are currently tested with computer simulations, since true biological phylogenies are unknown. Here, Randall et al.build an experimental phylogeny to benchmark the performance of alternate ancestral sequence reconstruction algorithms in inferring ancestral genotypes and phenotypes.
format article
author Ryan N. Randall
Caelan E. Radford
Kelsey A. Roof
Divya K. Natarajan
Eric A. Gaucher
author_facet Ryan N. Randall
Caelan E. Radford
Kelsey A. Roof
Divya K. Natarajan
Eric A. Gaucher
author_sort Ryan N. Randall
title An experimental phylogeny to benchmark ancestral sequence reconstruction
title_short An experimental phylogeny to benchmark ancestral sequence reconstruction
title_full An experimental phylogeny to benchmark ancestral sequence reconstruction
title_fullStr An experimental phylogeny to benchmark ancestral sequence reconstruction
title_full_unstemmed An experimental phylogeny to benchmark ancestral sequence reconstruction
title_sort experimental phylogeny to benchmark ancestral sequence reconstruction
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/8d76cf698a8e469bb081b9dabe390bf7
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