Correlation between optic nerve head structural parameters and glaucomatous visual field indices

Kyoichi Mizumoto,1 Masahiko Gosho,2 Masahiro Zako1 1Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan; 2Advanced Medical Research Center, Aichi Medical University, Nagakute, Aichi, Japan Abstract: We examined associations between optic nerve head structural parameters...

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Autores principales:	Mizumoto K, Gosho M, Zako M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/8d810216b7b14a9dbe703da45313f6db
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spelling	oai:doaj.org-article:8d810216b7b14a9dbe703da45313f6db2021-12-02T01:18:54ZCorrelation between optic nerve head structural parameters and glaucomatous visual field indices1177-5483https://doaj.org/article/8d810216b7b14a9dbe703da45313f6db2014-06-01T00:00:00Zhttp://www.dovepress.com/correlation-between-optic-nerve-head-structural-parameters-and-glaucom-a17356https://doaj.org/toc/1177-5483 Kyoichi Mizumoto,1 Masahiko Gosho,2 Masahiro Zako1 1Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan; 2Advanced Medical Research Center, Aichi Medical University, Nagakute, Aichi, Japan Abstract: We examined associations between optic nerve head structural parameters and glaucomatous visual field indices. The study population included patients with glaucomatous optic neuropathy who were evaluated at Aichi Medical University, Nagakute, Aichi, Japan, from October 2010 to January 2011. A total of 57 eyes from 33 patients were assessed. We measured visual field using a Humphrey field analyzer, peripapillary retinal nerve fiber layer thickness (RNFL-T), and Bruch’s membrane opening-minimum rim width (BMO-MRW) using spectral domain optical coherence tomography, and rim area with referring three-dimensional photography. Spearman’s rank correlation coefficients were calculated between the threshold of visual sensitivity or total deviation of visual field and the following five optic nerve head structural parameters: RNFL-T length, BMO-MRW length, rim area, and calculated RNFL-T and BMO-MRW volumes (each length multiplied by rim area). The Akaike information criterion was calculated to determine which structural parameter was the best predictor of each visual field index. Threshold of visual sensitivity had correlation coefficients of 0.23 with global sector of RNFL-T, 0.32 with BMO-MRW, 0.14 with rim area, 0.21 with RNFL-T volume, and 0.26 with BMO-MRW volume. The correlation coefficients for each parameter with total deviation of visual field were 0.22, 0.33, 0.28, 0.36, and 0.37, respectively. The Akaike information criterion of BMO-MRW showed the smallest values in analyses of both threshold of visual sensitivity and total deviation. The present results show that RNFL-T volume and BMO-MRW volume were more strongly correlated with total deviation than BMO-MRW, but BMO-MRW appeared to be the best predictor of the two glaucomatous visual field indices. Keywords: Bruch’s membrane opening-minimum rim width, glaucoma, retinal nerve fiber layer thickness, rim area, spectral domain optical coherence tomography, visual fieldMizumoto KGosho MZako MDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 1203-1208 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Mizumoto K Gosho M Zako M Correlation between optic nerve head structural parameters and glaucomatous visual field indices
description	Kyoichi Mizumoto,1 Masahiko Gosho,2 Masahiro Zako1 1Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan; 2Advanced Medical Research Center, Aichi Medical University, Nagakute, Aichi, Japan Abstract: We examined associations between optic nerve head structural parameters and glaucomatous visual field indices. The study population included patients with glaucomatous optic neuropathy who were evaluated at Aichi Medical University, Nagakute, Aichi, Japan, from October 2010 to January 2011. A total of 57 eyes from 33 patients were assessed. We measured visual field using a Humphrey field analyzer, peripapillary retinal nerve fiber layer thickness (RNFL-T), and Bruch’s membrane opening-minimum rim width (BMO-MRW) using spectral domain optical coherence tomography, and rim area with referring three-dimensional photography. Spearman’s rank correlation coefficients were calculated between the threshold of visual sensitivity or total deviation of visual field and the following five optic nerve head structural parameters: RNFL-T length, BMO-MRW length, rim area, and calculated RNFL-T and BMO-MRW volumes (each length multiplied by rim area). The Akaike information criterion was calculated to determine which structural parameter was the best predictor of each visual field index. Threshold of visual sensitivity had correlation coefficients of 0.23 with global sector of RNFL-T, 0.32 with BMO-MRW, 0.14 with rim area, 0.21 with RNFL-T volume, and 0.26 with BMO-MRW volume. The correlation coefficients for each parameter with total deviation of visual field were 0.22, 0.33, 0.28, 0.36, and 0.37, respectively. The Akaike information criterion of BMO-MRW showed the smallest values in analyses of both threshold of visual sensitivity and total deviation. The present results show that RNFL-T volume and BMO-MRW volume were more strongly correlated with total deviation than BMO-MRW, but BMO-MRW appeared to be the best predictor of the two glaucomatous visual field indices. Keywords: Bruch’s membrane opening-minimum rim width, glaucoma, retinal nerve fiber layer thickness, rim area, spectral domain optical coherence tomography, visual field
format	article
author	Mizumoto K Gosho M Zako M
author_facet	Mizumoto K Gosho M Zako M
author_sort	Mizumoto K
title	Correlation between optic nerve head structural parameters and glaucomatous visual field indices
title_short	Correlation between optic nerve head structural parameters and glaucomatous visual field indices
title_full	Correlation between optic nerve head structural parameters and glaucomatous visual field indices
title_fullStr	Correlation between optic nerve head structural parameters and glaucomatous visual field indices
title_full_unstemmed	Correlation between optic nerve head structural parameters and glaucomatous visual field indices
title_sort	correlation between optic nerve head structural parameters and glaucomatous visual field indices
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/8d810216b7b14a9dbe703da45313f6db
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_version_	1718403149465649152

Correlation between optic nerve head structural parameters and glaucomatous visual field indices

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