Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study

Elias Chelala,1 Hala El Rami,1 Ali Dirani,1 Ali Fadlallah,1 Omar Fakhoury,1 Elias Warrak2 1Saint-Joseph University, Faculty of Medicine, 2Clemenceau Medical Center, Beirut, Lebanon Background: The purpose of this study was to evaluate the visual outcome of photorefractive keratectomy (PRK) in patien...

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Autores principales: Chelala E, Rami HE, Dirani A, Fadlallah A, Fakhoury O, Warrak E
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Publicado: Dove Medical Press 2013
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spelling oai:doaj.org-article:8d99c600480447d3a2f0ad3dfadb93872021-12-02T02:37:49ZPhotorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study1177-54671177-5483https://doaj.org/article/8d99c600480447d3a2f0ad3dfadb93872013-09-01T00:00:00Zhttp://www.dovepress.com/photorefractive-keratectomy-in-patients-with-mild-to-moderate-stable-k-a14488https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Elias Chelala,1 Hala El Rami,1 Ali Dirani,1 Ali Fadlallah,1 Omar Fakhoury,1 Elias Warrak2 1Saint-Joseph University, Faculty of Medicine, 2Clemenceau Medical Center, Beirut, Lebanon Background: The purpose of this study was to evaluate the visual outcome of photorefractive keratectomy (PRK) in patients with mild to moderate stable keratoconus and to assess the risk of progression of the disease after the excimer laser procedure. Methods: In this prospective study, carried out at the Clemenceau Medical Center, an affiliate of Johns Hopkins International, in Beirut, Lebanon, 119 eyes from 72 patients with grade 1&ndash;2 keratoconus (Amsler&ndash;Krumeich classification) underwent PRK. Forty-seven patients had both eyes treated and 25 patients had one eye treated. The procedure was done using the Wavelight Eye Q Excimer laser. Uncorrected and best-corrected visual acuity, corneal topography, and pachymetry were assessed before the procedure and 3, 6, 12, 36, and 60 months after the procedure. Results: Mean uncorrected visual acuity showed a statistically significant improvement (P < 0.05) at one, 3, and 5 years follow-up. One hundred and seventeen eyes (98.3%) showed no progression while two eyes (1.7%) showed progression of the disease at 5 years follow-up, as documented by corneal topography and pachymetry. These two eyes were treated with corneal collagen crosslinking. Conclusion: PRK in mild to moderate keratoconus is a safe and effective procedure for improving uncorrected vision in patients with mild refractive errors. However, close follow-up of patients is needed to detect any progression of the disease. Longer follow-up is needed to assess the overall effect of this procedure on progression of the disease. Keywords: stable keratoconus, photorefractive keratectomyChelala ERami HEDirani AFadlallah AFakhoury OWarrak EDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1923-1928 (2013)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Chelala E
Rami HE
Dirani A
Fadlallah A
Fakhoury O
Warrak E
Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study
description Elias Chelala,1 Hala El Rami,1 Ali Dirani,1 Ali Fadlallah,1 Omar Fakhoury,1 Elias Warrak2 1Saint-Joseph University, Faculty of Medicine, 2Clemenceau Medical Center, Beirut, Lebanon Background: The purpose of this study was to evaluate the visual outcome of photorefractive keratectomy (PRK) in patients with mild to moderate stable keratoconus and to assess the risk of progression of the disease after the excimer laser procedure. Methods: In this prospective study, carried out at the Clemenceau Medical Center, an affiliate of Johns Hopkins International, in Beirut, Lebanon, 119 eyes from 72 patients with grade 1&ndash;2 keratoconus (Amsler&ndash;Krumeich classification) underwent PRK. Forty-seven patients had both eyes treated and 25 patients had one eye treated. The procedure was done using the Wavelight Eye Q Excimer laser. Uncorrected and best-corrected visual acuity, corneal topography, and pachymetry were assessed before the procedure and 3, 6, 12, 36, and 60 months after the procedure. Results: Mean uncorrected visual acuity showed a statistically significant improvement (P < 0.05) at one, 3, and 5 years follow-up. One hundred and seventeen eyes (98.3%) showed no progression while two eyes (1.7%) showed progression of the disease at 5 years follow-up, as documented by corneal topography and pachymetry. These two eyes were treated with corneal collagen crosslinking. Conclusion: PRK in mild to moderate keratoconus is a safe and effective procedure for improving uncorrected vision in patients with mild refractive errors. However, close follow-up of patients is needed to detect any progression of the disease. Longer follow-up is needed to assess the overall effect of this procedure on progression of the disease. Keywords: stable keratoconus, photorefractive keratectomy
format article
author Chelala E
Rami HE
Dirani A
Fadlallah A
Fakhoury O
Warrak E
author_facet Chelala E
Rami HE
Dirani A
Fadlallah A
Fakhoury O
Warrak E
author_sort Chelala E
title Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study
title_short Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study
title_full Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study
title_fullStr Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study
title_full_unstemmed Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study
title_sort photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/8d99c600480447d3a2f0ad3dfadb9387
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