Inference and effects of barcode multiplets in droplet-based single-cell assays

It is assumed that single-cell analyses capture one barcode per cell. Here, the authors show that up to 21% of cell barcodes on the 10X Chromium scATAC-seq assay may be derived from barcode multiplets.

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Autores principales:	Caleb A. Lareau, Sai Ma, Fabiana M. Duarte, Jason D. Buenrostro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8d9d4ceede554e67a58633816a18d4ba
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spelling	oai:doaj.org-article:8d9d4ceede554e67a58633816a18d4ba2021-12-02T14:40:52ZInference and effects of barcode multiplets in droplet-based single-cell assays10.1038/s41467-020-14667-52041-1723https://doaj.org/article/8d9d4ceede554e67a58633816a18d4ba2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14667-5https://doaj.org/toc/2041-1723It is assumed that single-cell analyses capture one barcode per cell. Here, the authors show that up to 21% of cell barcodes on the 10X Chromium scATAC-seq assay may be derived from barcode multiplets.Caleb A. LareauSai MaFabiana M. DuarteJason D. BuenrostroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Caleb A. Lareau Sai Ma Fabiana M. Duarte Jason D. Buenrostro Inference and effects of barcode multiplets in droplet-based single-cell assays
description	It is assumed that single-cell analyses capture one barcode per cell. Here, the authors show that up to 21% of cell barcodes on the 10X Chromium scATAC-seq assay may be derived from barcode multiplets.
format	article
author	Caleb A. Lareau Sai Ma Fabiana M. Duarte Jason D. Buenrostro
author_facet	Caleb A. Lareau Sai Ma Fabiana M. Duarte Jason D. Buenrostro
author_sort	Caleb A. Lareau
title	Inference and effects of barcode multiplets in droplet-based single-cell assays
title_short	Inference and effects of barcode multiplets in droplet-based single-cell assays
title_full	Inference and effects of barcode multiplets in droplet-based single-cell assays
title_fullStr	Inference and effects of barcode multiplets in droplet-based single-cell assays
title_full_unstemmed	Inference and effects of barcode multiplets in droplet-based single-cell assays
title_sort	inference and effects of barcode multiplets in droplet-based single-cell assays
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8d9d4ceede554e67a58633816a18d4ba
work_keys_str_mv	AT calebalareau inferenceandeffectsofbarcodemultipletsindropletbasedsinglecellassays AT saima inferenceandeffectsofbarcodemultipletsindropletbasedsinglecellassays AT fabianamduarte inferenceandeffectsofbarcodemultipletsindropletbasedsinglecellassays AT jasondbuenrostro inferenceandeffectsofbarcodemultipletsindropletbasedsinglecellassays
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Inference and effects of barcode multiplets in droplet-based single-cell assays

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