Probing the role of the residues in the active site of the transaminase from Thermobaculum terrenum.
Creating biocatalysts for (R)-selective amination effectively is highly desirable in organic synthesis. Despite noticeable progress in the engineering of (R)-amine activity in pyridoxal-5'-phosphate-dependent transaminases of fold type IV, the specialization of the activity is still an intuitiv...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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Acceso en línea: | https://doaj.org/article/8d9e7e54227c47c895f595f8bffbc68c |
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