Probing the role of the residues in the active site of the transaminase from Thermobaculum terrenum.
Creating biocatalysts for (R)-selective amination effectively is highly desirable in organic synthesis. Despite noticeable progress in the engineering of (R)-amine activity in pyridoxal-5'-phosphate-dependent transaminases of fold type IV, the specialization of the activity is still an intuitiv...
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Auteurs principaux: | Ekaterina Yu Bezsudnova, Alena Yu Nikolaeva, Alina K Bakunova, Tatiana V Rakitina, Dmitry A Suplatov, Vladimir O Popov, Konstantin M Boyko |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/8d9e7e54227c47c895f595f8bffbc68c |
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