Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study

Although recent evidence shows that the programmed intermittent epidural bolus can provide improved analgesia compared to continuous epidural infusion during labor, its usefulness in major upper abdominal surgery remains unclear. We evaluated the effect of programmed intermittent epidural bolus vers...

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Autores principales:	Yeon-Ju Kim, Do-Kyeong Lee, Hyun-Jung Kwon, Hye-Mee Kwon, Jong-Hyuk Lee, Doo-Hwan Kim, Sung-Moon Jeong
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	programmed intermittent epidural bolus continuous epidural infusion upper abdominal surgery epidural anesthesia postoperative analgesia Medicine R
Acceso en línea:	https://doaj.org/article/8da6f3712a13453286d33da28a16379d
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spelling	oai:doaj.org-article:8da6f3712a13453286d33da28a16379d2021-11-25T18:02:16ZProgrammed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study10.3390/jcm102253822077-0383https://doaj.org/article/8da6f3712a13453286d33da28a16379d2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5382https://doaj.org/toc/2077-0383Although recent evidence shows that the programmed intermittent epidural bolus can provide improved analgesia compared to continuous epidural infusion during labor, its usefulness in major upper abdominal surgery remains unclear. We evaluated the effect of programmed intermittent epidural bolus versus continuous epidural infusion on the consumption of postoperative rescue opioids, pain intensity, and consumption of local anesthetic by retrospective analysis of data of patients who underwent major upper abdominal surgery under ultrasound-assisted thoracic epidural analgesia between July 2018 and October 2020. The primary outcome was total opioid consumption up to 72 h after surgery. The data of postoperative pain scores, epidural local anesthetic consumption, and adverse events from 193 patients were analyzed (continuous epidural infusion: <i>n</i> = 124, programmed intermittent epidural bolus: <i>n</i> = 69). There was no significant difference in the rescue opioid consumption in the 72 h postoperative period between the groups (33.3 mg [20.0–43.3] vs. 28.3 mg [18.3–43.3], <i>p</i> = 0.375). There were also no significant differences in the pain scores, epidural local anesthetic consumption, and incidence of adverse events. Our findings suggest that the quality of postoperative analgesia and safety following major upper abdominal surgery were comparable between the groups. However, the use of programmed intermittent epidural bolus requires further evaluation.Yeon-Ju KimDo-Kyeong LeeHyun-Jung KwonHye-Mee KwonJong-Hyuk LeeDoo-Hwan KimSung-Moon JeongMDPI AGarticleprogrammed intermittent epidural boluscontinuous epidural infusionupper abdominal surgeryepidural anesthesiapostoperative analgesiaMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5382, p 5382 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	programmed intermittent epidural bolus continuous epidural infusion upper abdominal surgery epidural anesthesia postoperative analgesia Medicine R
spellingShingle	programmed intermittent epidural bolus continuous epidural infusion upper abdominal surgery epidural anesthesia postoperative analgesia Medicine R Yeon-Ju Kim Do-Kyeong Lee Hyun-Jung Kwon Hye-Mee Kwon Jong-Hyuk Lee Doo-Hwan Kim Sung-Moon Jeong Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study
description	Although recent evidence shows that the programmed intermittent epidural bolus can provide improved analgesia compared to continuous epidural infusion during labor, its usefulness in major upper abdominal surgery remains unclear. We evaluated the effect of programmed intermittent epidural bolus versus continuous epidural infusion on the consumption of postoperative rescue opioids, pain intensity, and consumption of local anesthetic by retrospective analysis of data of patients who underwent major upper abdominal surgery under ultrasound-assisted thoracic epidural analgesia between July 2018 and October 2020. The primary outcome was total opioid consumption up to 72 h after surgery. The data of postoperative pain scores, epidural local anesthetic consumption, and adverse events from 193 patients were analyzed (continuous epidural infusion: <i>n</i> = 124, programmed intermittent epidural bolus: <i>n</i> = 69). There was no significant difference in the rescue opioid consumption in the 72 h postoperative period between the groups (33.3 mg [20.0–43.3] vs. 28.3 mg [18.3–43.3], <i>p</i> = 0.375). There were also no significant differences in the pain scores, epidural local anesthetic consumption, and incidence of adverse events. Our findings suggest that the quality of postoperative analgesia and safety following major upper abdominal surgery were comparable between the groups. However, the use of programmed intermittent epidural bolus requires further evaluation.
format	article
author	Yeon-Ju Kim Do-Kyeong Lee Hyun-Jung Kwon Hye-Mee Kwon Jong-Hyuk Lee Doo-Hwan Kim Sung-Moon Jeong
author_facet	Yeon-Ju Kim Do-Kyeong Lee Hyun-Jung Kwon Hye-Mee Kwon Jong-Hyuk Lee Doo-Hwan Kim Sung-Moon Jeong
author_sort	Yeon-Ju Kim
title	Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study
title_short	Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study
title_full	Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study
title_fullStr	Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study
title_full_unstemmed	Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study
title_sort	programmed intermittent epidural bolus versus continuous epidural infusion in major upper abdominal surgery: a retrospective comparative study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8da6f3712a13453286d33da28a16379d
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Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study

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