The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype

Senescence-associated secretory phenotype (SASP) involves secretion of factors such as pro-inflammatory cytokines. Here the authors show that MIR31HG regulates the expression and secretion of a subset of SASP components that induce paracrine invasion, through interaction with YBX1 and induction of I...

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Autores principales:	Marta Montes, Michal Lubas, Frederic S. Arendrup, Bettina Mentz, Neha Rohatgi, Sarunas Tumas, Lea M. Harder, Anders J. Skanderup, Jens S. Andersen, Anders H. Lund
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8da6f54bfa9d4666b2534cafaba5a56a
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spelling	oai:doaj.org-article:8da6f54bfa9d4666b2534cafaba5a56a2021-12-02T16:55:32ZThe long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype10.1038/s41467-021-22746-42041-1723https://doaj.org/article/8da6f54bfa9d4666b2534cafaba5a56a2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22746-4https://doaj.org/toc/2041-1723Senescence-associated secretory phenotype (SASP) involves secretion of factors such as pro-inflammatory cytokines. Here the authors show that MIR31HG regulates the expression and secretion of a subset of SASP components that induce paracrine invasion, through interaction with YBX1 and induction of IL1A translation.Marta MontesMichal LubasFrederic S. ArendrupBettina MentzNeha RohatgiSarunas TumasLea M. HarderAnders J. SkanderupJens S. AndersenAnders H. LundNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marta Montes Michal Lubas Frederic S. Arendrup Bettina Mentz Neha Rohatgi Sarunas Tumas Lea M. Harder Anders J. Skanderup Jens S. Andersen Anders H. Lund The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype
description	Senescence-associated secretory phenotype (SASP) involves secretion of factors such as pro-inflammatory cytokines. Here the authors show that MIR31HG regulates the expression and secretion of a subset of SASP components that induce paracrine invasion, through interaction with YBX1 and induction of IL1A translation.
format	article
author	Marta Montes Michal Lubas Frederic S. Arendrup Bettina Mentz Neha Rohatgi Sarunas Tumas Lea M. Harder Anders J. Skanderup Jens S. Andersen Anders H. Lund
author_facet	Marta Montes Michal Lubas Frederic S. Arendrup Bettina Mentz Neha Rohatgi Sarunas Tumas Lea M. Harder Anders J. Skanderup Jens S. Andersen Anders H. Lund
author_sort	Marta Montes
title	The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype
title_short	The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype
title_full	The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype
title_fullStr	The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype
title_full_unstemmed	The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype
title_sort	long non-coding rna mir31hg regulates the senescence associated secretory phenotype
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8da6f54bfa9d4666b2534cafaba5a56a
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The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype

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