Membrane mediated toppling mechanism of the folate energy coupling factor transporter

Energy coupling factor (ECF) transporters are responsible for the uptake of micronutrients and consist of an integral membrane unit, the S-component, which confers substrate specificity. Here, authors present multi-scale molecular dynamics simulations and in vitro experiments to study the molecular...

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Autores principales:	Ignacio Faustino, Haleh Abdizadeh, Paulo C. T. Souza, Aike Jeucken, Weronika K. Stanek, Albert Guskov, Dirk J. Slotboom, Siewert J. Marrink
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8db3b4bf1fbd48c08e8894be97681363
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spelling	oai:doaj.org-article:8db3b4bf1fbd48c08e8894be976813632021-12-02T14:42:16ZMembrane mediated toppling mechanism of the folate energy coupling factor transporter10.1038/s41467-020-15554-92041-1723https://doaj.org/article/8db3b4bf1fbd48c08e8894be976813632020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15554-9https://doaj.org/toc/2041-1723Energy coupling factor (ECF) transporters are responsible for the uptake of micronutrients and consist of an integral membrane unit, the S-component, which confers substrate specificity. Here, authors present multi-scale molecular dynamics simulations and in vitro experiments to study the molecular toppling mechanism of the S-component of a folate-specific ECF transporter.Ignacio FaustinoHaleh AbdizadehPaulo C. T. SouzaAike JeuckenWeronika K. StanekAlbert GuskovDirk J. SlotboomSiewert J. MarrinkNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ignacio Faustino Haleh Abdizadeh Paulo C. T. Souza Aike Jeucken Weronika K. Stanek Albert Guskov Dirk J. Slotboom Siewert J. Marrink Membrane mediated toppling mechanism of the folate energy coupling factor transporter
description	Energy coupling factor (ECF) transporters are responsible for the uptake of micronutrients and consist of an integral membrane unit, the S-component, which confers substrate specificity. Here, authors present multi-scale molecular dynamics simulations and in vitro experiments to study the molecular toppling mechanism of the S-component of a folate-specific ECF transporter.
format	article
author	Ignacio Faustino Haleh Abdizadeh Paulo C. T. Souza Aike Jeucken Weronika K. Stanek Albert Guskov Dirk J. Slotboom Siewert J. Marrink
author_facet	Ignacio Faustino Haleh Abdizadeh Paulo C. T. Souza Aike Jeucken Weronika K. Stanek Albert Guskov Dirk J. Slotboom Siewert J. Marrink
author_sort	Ignacio Faustino
title	Membrane mediated toppling mechanism of the folate energy coupling factor transporter
title_short	Membrane mediated toppling mechanism of the folate energy coupling factor transporter
title_full	Membrane mediated toppling mechanism of the folate energy coupling factor transporter
title_fullStr	Membrane mediated toppling mechanism of the folate energy coupling factor transporter
title_full_unstemmed	Membrane mediated toppling mechanism of the folate energy coupling factor transporter
title_sort	membrane mediated toppling mechanism of the folate energy coupling factor transporter
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8db3b4bf1fbd48c08e8894be97681363
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_version_	1718389764912054272

Membrane mediated toppling mechanism of the folate energy coupling factor transporter

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