Pre-transplant donor-reactive IL-21 producing T cells as a tool to identify an increased risk for acute rejection

Abstract Pre-transplant screening focuses on the detection of anti-HLA alloantibodies. Previous studies have shown that IFN-γ and IL-21 producing T cells are associated with the development of acute rejection (AR). The aim of this study, was to assess whether pre-transplant donor-reactive T cells an...

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Autores principales: Aleixandra Mendoza Rojas, Teun van Gelder, Ronella de Kuiper, Derek Reijerkerk, Marian C. Clahsen-van Groningen, Dennis A. Hesselink, Carla C. Baan, Nicole M. van Besouw
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8db403cdf73c4b05a4654cd6a3cdb0e9
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