Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration.

Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration.

Signal-induced transcript isoform variation (TIV) includes alternative promoter usage as well as alternative splicing and alternative polyadenylation of mRNA. To assess the phenotypic relevance of signal-induced TIV, we employed exon arrays and breast epithelial cells, which migrate in response to t...

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Autores principales: Wolfgang J Köstler, Amit Zeisel, Cindy Körner, Jonathan M Tsai, Jasmine Jacob-Hirsch, Nir Ben-Chetrit, Kirti Sharma, Hadas Cohen-Dvashi, Assif Yitzhaky, Eric Lader, Ulrich Tschulena, Gideon Rechavi, Eytan Domany, Stefan Wiemann, Yosef Yarden
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8dbbe8b824c347ce9935b0151b528bff
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