Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach.

Bacteriorhodopsin has a polar cluster of amino acids surrounding the retinal molecule, which is responsible for light harvesting to fuel proton pumping. From our previous studies, we have shown that threonine 90 is the pivotal amino acid in this polar cluster, both functionally and structurally. In...

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Autores principales: Rosana Simón-Vázquez, Marta Domínguez, Víctor A Lórenz-Fonfría, Susana Alvarez, José-Luís Bourdelande, Angel R de Lera, Esteve Padrós, Alex Perálvarez-Marín
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/8dbfd59be4ea49ff9d2753dd0fd882cf
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