Order and stochasticity in the folding of individual Drosophila genomes

Genomes are partitioned into topologically associating domains (TADs). Here the authors present single-nucleus Hi-C maps in Drosophila at 10 kb resolution, demonstrating the presence of chromatin compartments in individual nuclei, and partitioning of the genome into non-hierarchical TADs at the scal...

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Autores principales:	Sergey V. Ulianov, Vlada V. Zakharova, Aleksandra A. Galitsyna, Pavel I. Kos, Kirill E. Polovnikov, Ilya M. Flyamer, Elena A. Mikhaleva, Ekaterina E. Khrameeva, Diego Germini, Mariya D. Logacheva, Alexey A. Gavrilov, Alexander S. Gorsky, Sergey K. Nechaev, Mikhail S. Gelfand, Yegor S. Vassetzky, Alexander V. Chertovich, Yuri Y. Shevelyov, Sergey V. Razin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8dcfb2d70fc24ab89ca4dad46c6324c9
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spelling	oai:doaj.org-article:8dcfb2d70fc24ab89ca4dad46c6324c92021-12-02T15:08:00ZOrder and stochasticity in the folding of individual Drosophila genomes10.1038/s41467-020-20292-z2041-1723https://doaj.org/article/8dcfb2d70fc24ab89ca4dad46c6324c92021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20292-zhttps://doaj.org/toc/2041-1723Genomes are partitioned into topologically associating domains (TADs). Here the authors present single-nucleus Hi-C maps in Drosophila at 10 kb resolution, demonstrating the presence of chromatin compartments in individual nuclei, and partitioning of the genome into non-hierarchical TADs at the scale of 100 kb, which resembles population TAD profiles.Sergey V. UlianovVlada V. ZakharovaAleksandra A. GalitsynaPavel I. KosKirill E. PolovnikovIlya M. FlyamerElena A. MikhalevaEkaterina E. KhrameevaDiego GerminiMariya D. LogachevaAlexey A. GavrilovAlexander S. GorskySergey K. NechaevMikhail S. GelfandYegor S. VassetzkyAlexander V. ChertovichYuri Y. ShevelyovSergey V. RazinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sergey V. Ulianov Vlada V. Zakharova Aleksandra A. Galitsyna Pavel I. Kos Kirill E. Polovnikov Ilya M. Flyamer Elena A. Mikhaleva Ekaterina E. Khrameeva Diego Germini Mariya D. Logacheva Alexey A. Gavrilov Alexander S. Gorsky Sergey K. Nechaev Mikhail S. Gelfand Yegor S. Vassetzky Alexander V. Chertovich Yuri Y. Shevelyov Sergey V. Razin Order and stochasticity in the folding of individual Drosophila genomes
description	Genomes are partitioned into topologically associating domains (TADs). Here the authors present single-nucleus Hi-C maps in Drosophila at 10 kb resolution, demonstrating the presence of chromatin compartments in individual nuclei, and partitioning of the genome into non-hierarchical TADs at the scale of 100 kb, which resembles population TAD profiles.
format	article
author	Sergey V. Ulianov Vlada V. Zakharova Aleksandra A. Galitsyna Pavel I. Kos Kirill E. Polovnikov Ilya M. Flyamer Elena A. Mikhaleva Ekaterina E. Khrameeva Diego Germini Mariya D. Logacheva Alexey A. Gavrilov Alexander S. Gorsky Sergey K. Nechaev Mikhail S. Gelfand Yegor S. Vassetzky Alexander V. Chertovich Yuri Y. Shevelyov Sergey V. Razin
author_facet	Sergey V. Ulianov Vlada V. Zakharova Aleksandra A. Galitsyna Pavel I. Kos Kirill E. Polovnikov Ilya M. Flyamer Elena A. Mikhaleva Ekaterina E. Khrameeva Diego Germini Mariya D. Logacheva Alexey A. Gavrilov Alexander S. Gorsky Sergey K. Nechaev Mikhail S. Gelfand Yegor S. Vassetzky Alexander V. Chertovich Yuri Y. Shevelyov Sergey V. Razin
author_sort	Sergey V. Ulianov
title	Order and stochasticity in the folding of individual Drosophila genomes
title_short	Order and stochasticity in the folding of individual Drosophila genomes
title_full	Order and stochasticity in the folding of individual Drosophila genomes
title_fullStr	Order and stochasticity in the folding of individual Drosophila genomes
title_full_unstemmed	Order and stochasticity in the folding of individual Drosophila genomes
title_sort	order and stochasticity in the folding of individual drosophila genomes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8dcfb2d70fc24ab89ca4dad46c6324c9
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Order and stochasticity in the folding of individual Drosophila genomes

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