Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris

Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris

Microglia, the resident phagocytes of the central nervous system and one of the key modulators of the innate immune system, have been shown to play a major role in brain insults. Upon activation in response to neuroinflammation, microglia promote the release of inflammatory mediators as well as prom...

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Autores principales: Aneese A. Jaffa, Miran A. Jaffa, Mayssam Moussa, Ibrahim A. Ahmed, Mia Karam, Kawthar Sharaf Aldeen, Rola Al Sayegh, Ghewa A. El-Achkar, Leila Nasrallah, Yara Yehya, Aida Habib, Fuad N. Ziyadeh, Ali H. Eid, Firas H. Kobeissy, Ayad A. Jaffa
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
neuroinflammation
cytokines
plasma kallikrein-kinin system
protease-activated receptor 2
bradykinin 2 receptor
interactome
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/8dd264650da5460bb2dfd713f8d2f363
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https://doaj.org/article/8dd264650da5460bb2dfd713f8d2f363

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