Individual with subclinical atherosclerosis have impaired proliferation of blood outgrowth endothelial cells, which can be restored by statin therapy.

<h4>Background</h4>To study the regenerative capacity of the endothelium in patients with coronary artery disease (CAD), we cultured blood outgrowth endothelial cells (BOECs) of patients with premature CAD and their first degree relatives (FDR). Additionally we evaluated the influence of...

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Auteurs principaux: Javier Martin-Ramirez, Maayke G M Kok, Menno Hofman, Ruben Bierings, Esther E Creemers, Joost C M Meijers, Jan Voorberg, Sara-Joan Pinto-Sietsma
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Q
Accès en ligne:https://doaj.org/article/8dd3ffb311cb49b8b7e49f935ec63a9e
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