Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids

Despite the progress in C(sp3) cross-coupling reactions, full control over the stereochemistry remains a challenge. Here, the authors show that phosphine-containing axially shielded Pd(II) complexes enable Suzuki-Miyaura cross-couplings of unactivated C(sp3) boronic acids with perfect stereoretentio...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jonathan W. Lehmann, Ian T. Crouch, Daniel J. Blair, Melanie Trobe, Pulin Wang, Junqi Li, Martin D. Burke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8dd4c2e0a80b4f308053aec58a157f12
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8dd4c2e0a80b4f308053aec58a157f12
record_format	dspace
spelling	oai:doaj.org-article:8dd4c2e0a80b4f308053aec58a157f122021-12-02T16:57:51ZAxial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids10.1038/s41467-019-09249-z2041-1723https://doaj.org/article/8dd4c2e0a80b4f308053aec58a157f122019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09249-zhttps://doaj.org/toc/2041-1723Despite the progress in C(sp3) cross-coupling reactions, full control over the stereochemistry remains a challenge. Here, the authors show that phosphine-containing axially shielded Pd(II) complexes enable Suzuki-Miyaura cross-couplings of unactivated C(sp3) boronic acids with perfect stereoretention.Jonathan W. LehmannIan T. CrouchDaniel J. BlairMelanie TrobePulin WangJunqi LiMartin D. BurkeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jonathan W. Lehmann Ian T. Crouch Daniel J. Blair Melanie Trobe Pulin Wang Junqi Li Martin D. Burke Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids
description	Despite the progress in C(sp3) cross-coupling reactions, full control over the stereochemistry remains a challenge. Here, the authors show that phosphine-containing axially shielded Pd(II) complexes enable Suzuki-Miyaura cross-couplings of unactivated C(sp3) boronic acids with perfect stereoretention.
format	article
author	Jonathan W. Lehmann Ian T. Crouch Daniel J. Blair Melanie Trobe Pulin Wang Junqi Li Martin D. Burke
author_facet	Jonathan W. Lehmann Ian T. Crouch Daniel J. Blair Melanie Trobe Pulin Wang Junqi Li Martin D. Burke
author_sort	Jonathan W. Lehmann
title	Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids
title_short	Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids
title_full	Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids
title_fullStr	Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids
title_full_unstemmed	Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids
title_sort	axial shielding of pd(ii) complexes enables perfect stereoretention in suzuki-miyaura cross-coupling of csp3 boronic acids
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8dd4c2e0a80b4f308053aec58a157f12
work_keys_str_mv	AT jonathanwlehmann axialshieldingofpdiicomplexesenablesperfectstereoretentioninsuzukimiyauracrosscouplingofcsp3boronicacids AT iantcrouch axialshieldingofpdiicomplexesenablesperfectstereoretentioninsuzukimiyauracrosscouplingofcsp3boronicacids AT danieljblair axialshieldingofpdiicomplexesenablesperfectstereoretentioninsuzukimiyauracrosscouplingofcsp3boronicacids AT melanietrobe axialshieldingofpdiicomplexesenablesperfectstereoretentioninsuzukimiyauracrosscouplingofcsp3boronicacids AT pulinwang axialshieldingofpdiicomplexesenablesperfectstereoretentioninsuzukimiyauracrosscouplingofcsp3boronicacids AT junqili axialshieldingofpdiicomplexesenablesperfectstereoretentioninsuzukimiyauracrosscouplingofcsp3boronicacids AT martindburke axialshieldingofpdiicomplexesenablesperfectstereoretentioninsuzukimiyauracrosscouplingofcsp3boronicacids
_version_	1718382457932218368

Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids

Ejemplares similares