Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

Abstract Estrogen is critical for skeletal homeostasis and regulates bone remodeling, in part, by modulating the expression of receptor activator of NF-κB ligand (RANKL), an essential cytokine for bone resorption by osteoclasts. RANKL can be produced by a variety of hematopoietic (e.g. T and B-cell)...

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Autores principales: Carmen Streicher, Alexandra Heyny, Olena Andrukhova, Barbara Haigl, Svetlana Slavic, Christiane Schüler, Karoline Kollmann, Ingrid Kantner, Veronika Sexl, Miriam Kleiter, Lorenz C. Hofbauer, Paul J. Kostenuik, Reinhold G. Erben
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/8deacb25c8e6455ab90cd1d806872bfd
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