On the Use of Gene Ontology Annotations to Assess Functional Similarity among Orthologs and Paralogs: A Short Report.

A recent paper (Nehrt et al., PLoS Comput. Biol. 7:e1002073, 2011) has proposed a metric for the "functional similarity" between two genes that uses only the Gene Ontology (GO) annotations directly derived from published experimental results. Applying this metric, the authors concluded tha...

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Bibliographic Details
Main Authors: Paul D Thomas, Valerie Wood, Christopher J Mungall, Suzanna E Lewis, Judith A Blake, Gene Ontology Consortium
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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Online Access:https://doaj.org/article/8debaa70fca742d79a2e558d34f5d494
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