Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response

The bee venom melittin has anti-tumor properties but is unsuitable for therapeutic use on its own. Here, the authors generate melittin-nanoparticles and demonstrate that the nanoparticles reduce tumor growth and generate an anti-tumor immune response.

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Detalles Bibliográficos
Autores principales: Xiang Yu, Yanfeng Dai, Yifan Zhao, Shuhong Qi, Lei Liu, Lisen Lu, Qingming Luo, Zhihong Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8debd2644ced4e2d948948cd2bf86a07
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Sumario:The bee venom melittin has anti-tumor properties but is unsuitable for therapeutic use on its own. Here, the authors generate melittin-nanoparticles and demonstrate that the nanoparticles reduce tumor growth and generate an anti-tumor immune response.