Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response

The bee venom melittin has anti-tumor properties but is unsuitable for therapeutic use on its own. Here, the authors generate melittin-nanoparticles and demonstrate that the nanoparticles reduce tumor growth and generate an anti-tumor immune response.

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Autores principales:	Xiang Yu, Yanfeng Dai, Yifan Zhao, Shuhong Qi, Lei Liu, Lisen Lu, Qingming Luo, Zhihong Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8debd2644ced4e2d948948cd2bf86a07
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spelling	oai:doaj.org-article:8debd2644ced4e2d948948cd2bf86a072021-12-02T16:49:30ZMelittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response10.1038/s41467-020-14906-92041-1723https://doaj.org/article/8debd2644ced4e2d948948cd2bf86a072020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14906-9https://doaj.org/toc/2041-1723The bee venom melittin has anti-tumor properties but is unsuitable for therapeutic use on its own. Here, the authors generate melittin-nanoparticles and demonstrate that the nanoparticles reduce tumor growth and generate an anti-tumor immune response.Xiang YuYanfeng DaiYifan ZhaoShuhong QiLei LiuLisen LuQingming LuoZhihong ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiang Yu Yanfeng Dai Yifan Zhao Shuhong Qi Lei Liu Lisen Lu Qingming Luo Zhihong Zhang Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
description	The bee venom melittin has anti-tumor properties but is unsuitable for therapeutic use on its own. Here, the authors generate melittin-nanoparticles and demonstrate that the nanoparticles reduce tumor growth and generate an anti-tumor immune response.
format	article
author	Xiang Yu Yanfeng Dai Yifan Zhao Shuhong Qi Lei Liu Lisen Lu Qingming Luo Zhihong Zhang
author_facet	Xiang Yu Yanfeng Dai Yifan Zhao Shuhong Qi Lei Liu Lisen Lu Qingming Luo Zhihong Zhang
author_sort	Xiang Yu
title	Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
title_short	Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
title_full	Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
title_fullStr	Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
title_full_unstemmed	Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
title_sort	melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8debd2644ced4e2d948948cd2bf86a07
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Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response

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