Fine control of metal concentrations is necessary for cells to discern zinc from cobalt

Bacteria possess transcription factors whose DNA-binding activity is altered upon binding to specific metals, but the binding of metals is not specific in vitro. Here, Osman et al. show that tight regulation of buffered intracellular metal concentrations is a prerequisite for metal specificity.

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Detalles Bibliográficos
Autores principales: Deenah Osman, Andrew W. Foster, Junjun Chen, Kotryna Svedaite, Jonathan W. Steed, Elena Lurie-Luke, Thomas G. Huggins, Nigel J. Robinson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/8dee7c1b410044ad893a2b322b638933
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