Single intravitreal ranibizumab for myopic choroidal neovascularization

Saidin Nor-Masniwati, Ismail Shatriah, Embong ZunainaDepartment of Ophthalmology, Universiti Sains Malaysia, Kelantan, MalaysiaAbstract: We report a case of myopic choroidal neovascularization that showed improvement after a single injection of ranibizumab. A 45-year-old Chinese man with high myopia...

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Autores principales: Shatriah I, Nor-Masniwati S, Zunaina E
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Lenguaje:EN
Publicado: Dove Medical Press 2011
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spelling oai:doaj.org-article:8dfcc821f4b54f369c1fd6f45903fa642021-12-02T05:12:09ZSingle intravitreal ranibizumab for myopic choroidal neovascularization1177-54671177-5483https://doaj.org/article/8dfcc821f4b54f369c1fd6f45903fa642011-08-01T00:00:00Zhttp://www.dovepress.com/single-intravitreal-ranibizumab-for-myopic-choroidal-neovascularizatio-a8018https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Saidin Nor-Masniwati, Ismail Shatriah, Embong ZunainaDepartment of Ophthalmology, Universiti Sains Malaysia, Kelantan, MalaysiaAbstract: We report a case of myopic choroidal neovascularization that showed improvement after a single injection of ranibizumab. A 45-year-old Chinese man with high myopia presented with sudden onset painless central scotoma of his right eye of 2 weeks’ duration. There was no history of trauma. His right eye vision on presentation was 6/30 which showed no improvement with pinhole. The right fundus showed myopic maculopathy at the posterior pole with subretinal hemorrhage at the inferotemporal fovea. The optic disc was tilted with inferotemporal peripapillary atrophy. There was a myopic maculopathy appearance in the macula of the left eye. Fundus fluorescein angiography revealed choroidal neovascularization at the fovea of the right eye. A diagnosis of right eye choroidal neovascularization secondary to myopic maculopathy was made. A single intravitreal injection of ranibizumab 0.05 mL was given. Ten weeks following intravitreal injection, vision had improved to 6/7.5, and repeated fundus fluorescein angiography showed absence of choroidal neovascularization. Follow-up at 6 months showed visual acuity had normalized to 6/6 with glasses, which was maintained up to 12 months following treatment. The right fundus showed no further subretinal hemorrhage with no new lesions.Keywords: myopia, choroidal neovascularization, antivascular endothelial growth factorShatriah INor-Masniwati SZunaina EDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1079-1082 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Shatriah I
Nor-Masniwati S
Zunaina E
Single intravitreal ranibizumab for myopic choroidal neovascularization
description Saidin Nor-Masniwati, Ismail Shatriah, Embong ZunainaDepartment of Ophthalmology, Universiti Sains Malaysia, Kelantan, MalaysiaAbstract: We report a case of myopic choroidal neovascularization that showed improvement after a single injection of ranibizumab. A 45-year-old Chinese man with high myopia presented with sudden onset painless central scotoma of his right eye of 2 weeks’ duration. There was no history of trauma. His right eye vision on presentation was 6/30 which showed no improvement with pinhole. The right fundus showed myopic maculopathy at the posterior pole with subretinal hemorrhage at the inferotemporal fovea. The optic disc was tilted with inferotemporal peripapillary atrophy. There was a myopic maculopathy appearance in the macula of the left eye. Fundus fluorescein angiography revealed choroidal neovascularization at the fovea of the right eye. A diagnosis of right eye choroidal neovascularization secondary to myopic maculopathy was made. A single intravitreal injection of ranibizumab 0.05 mL was given. Ten weeks following intravitreal injection, vision had improved to 6/7.5, and repeated fundus fluorescein angiography showed absence of choroidal neovascularization. Follow-up at 6 months showed visual acuity had normalized to 6/6 with glasses, which was maintained up to 12 months following treatment. The right fundus showed no further subretinal hemorrhage with no new lesions.Keywords: myopia, choroidal neovascularization, antivascular endothelial growth factor
format article
author Shatriah I
Nor-Masniwati S
Zunaina E
author_facet Shatriah I
Nor-Masniwati S
Zunaina E
author_sort Shatriah I
title Single intravitreal ranibizumab for myopic choroidal neovascularization
title_short Single intravitreal ranibizumab for myopic choroidal neovascularization
title_full Single intravitreal ranibizumab for myopic choroidal neovascularization
title_fullStr Single intravitreal ranibizumab for myopic choroidal neovascularization
title_full_unstemmed Single intravitreal ranibizumab for myopic choroidal neovascularization
title_sort single intravitreal ranibizumab for myopic choroidal neovascularization
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/8dfcc821f4b54f369c1fd6f45903fa64
work_keys_str_mv AT shatriahi singleintravitrealranibizumabformyopicchoroidalneovascularization
AT normasniwatis singleintravitrealranibizumabformyopicchoroidalneovascularization
AT zunainae singleintravitrealranibizumabformyopicchoroidalneovascularization
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