Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules

The wide use of microfluidics for biological analysis demands scalable preparation methods, yet in practice it is very challenging. Here, Wanget al. show a wafer-scale fabrication of nanofluidic chips with single-digit nanometre dimension, which is compatible with standard semiconductor processing.

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Autores principales: Chao Wang, Sung-Wook Nam, John M. Cotte, Christopher V. Jahnes, Evan G. Colgan, Robert L. Bruce, Markus Brink, Michael F. Lofaro, Jyotica V. Patel, Lynne M. Gignac, Eric A. Joseph, Satyavolu Papa Rao, Gustavo Stolovitzky, Stanislav Polonsky, Qinghuang Lin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8dfe6382a6f3435d9401956b405c4b22
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spelling oai:doaj.org-article:8dfe6382a6f3435d9401956b405c4b222021-12-02T17:01:17ZWafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules10.1038/ncomms142432041-1723https://doaj.org/article/8dfe6382a6f3435d9401956b405c4b222017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14243https://doaj.org/toc/2041-1723The wide use of microfluidics for biological analysis demands scalable preparation methods, yet in practice it is very challenging. Here, Wanget al. show a wafer-scale fabrication of nanofluidic chips with single-digit nanometre dimension, which is compatible with standard semiconductor processing.Chao WangSung-Wook NamJohn M. CotteChristopher V. JahnesEvan G. ColganRobert L. BruceMarkus BrinkMichael F. LofaroJyotica V. PatelLynne M. GignacEric A. JosephSatyavolu Papa RaoGustavo StolovitzkyStanislav PolonskyQinghuang LinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chao Wang
Sung-Wook Nam
John M. Cotte
Christopher V. Jahnes
Evan G. Colgan
Robert L. Bruce
Markus Brink
Michael F. Lofaro
Jyotica V. Patel
Lynne M. Gignac
Eric A. Joseph
Satyavolu Papa Rao
Gustavo Stolovitzky
Stanislav Polonsky
Qinghuang Lin
Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules
description The wide use of microfluidics for biological analysis demands scalable preparation methods, yet in practice it is very challenging. Here, Wanget al. show a wafer-scale fabrication of nanofluidic chips with single-digit nanometre dimension, which is compatible with standard semiconductor processing.
format article
author Chao Wang
Sung-Wook Nam
John M. Cotte
Christopher V. Jahnes
Evan G. Colgan
Robert L. Bruce
Markus Brink
Michael F. Lofaro
Jyotica V. Patel
Lynne M. Gignac
Eric A. Joseph
Satyavolu Papa Rao
Gustavo Stolovitzky
Stanislav Polonsky
Qinghuang Lin
author_facet Chao Wang
Sung-Wook Nam
John M. Cotte
Christopher V. Jahnes
Evan G. Colgan
Robert L. Bruce
Markus Brink
Michael F. Lofaro
Jyotica V. Patel
Lynne M. Gignac
Eric A. Joseph
Satyavolu Papa Rao
Gustavo Stolovitzky
Stanislav Polonsky
Qinghuang Lin
author_sort Chao Wang
title Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules
title_short Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules
title_full Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules
title_fullStr Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules
title_full_unstemmed Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules
title_sort wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single dna molecules
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/8dfe6382a6f3435d9401956b405c4b22
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