Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults

Yuri Gustavo de Sousa Barbalho,1 Marina Morato Stival,1 Luciano Ramos de Lima,1 Izabel Cristina Rodrigues da Silva,1 Alessandro de Oliveira Silva,2 Manoela Vieira Gomes da Costa,1 Tania Cristina Morais Santa Barbara Rehem,1 Silvana Schwerz Funghetto1 1Graduate Department of Health Sciences and Techn...

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Autores principales:	Gustavo de Sousa Barbalho Y, Morato Stival M, Ramos de Lima L, Cristina Rodrigues da Silva I, de Oliveira Silva A, Vieira Gomes da Costa M, Cristina Morais Santa Barbara Rehem T, Schwerz Funghetto S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	aged metabolic syndrome cardiovascular system aging population Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/8e02b62f313c443baddbbaa67c60738e
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spelling	oai:doaj.org-article:8e02b62f313c443baddbbaa67c60738e2021-12-02T15:36:49ZImpact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults1178-1998https://doaj.org/article/8e02b62f313c443baddbbaa67c60738e2020-09-01T00:00:00Zhttps://www.dovepress.com/impact-of-metabolic-syndrome-components-in-high-risk-cardiovascular-di-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Yuri Gustavo de Sousa Barbalho,1 Marina Morato Stival,1 Luciano Ramos de Lima,1 Izabel Cristina Rodrigues da Silva,1 Alessandro de Oliveira Silva,2 Manoela Vieira Gomes da Costa,1 Tania Cristina Morais Santa Barbara Rehem,1 Silvana Schwerz Funghetto1 1Graduate Department of Health Sciences and Technologies, University of Brasilia (UnB), Brasilia, Federal District, Brazil; 2Physical Education Department, University Center of Brasilia, Brasilia, Federal District, BrazilCorrespondence: Yuri Gustavo de Sousa Barbalho Tel +55 61 9 9112-7116Email yurigustavo.sousa@gmail.comObjective: Analyze the influence between the components of metabolic syndrome and the independent risk for cardiovascular disease (CVD) in the elderly.Methods: A descriptive cross-sectional study was carried out with 205 older adults from a primary healthcare unit of the Federal District, Brazil. The cardiovascular risk was determined by the Framingham Risk Score (FRS). The National Cholesterol Evaluation Program for Adult Treatment Panel III 2001 (NCEP-ATP III) criteria were considered to analyze metabolic syndrome (MS) diagnoses.Results: There was a strong association between MS and high cardiovascular risk (OR = 8.86). The univariate analysis main findings revealed that male gender, diabetes, smoking habit, systolic blood pressure, HDL level, high blood glucose, glycated hemoglobin, and LDL level were associated with high cardiovascular risk. FRS increases significantly with the presence of four or more MS components (by 30%, if 4 components are present, and by 40%, if 5 components) when compared with the presence of three or fewer components (P < 0.001). A logistic regression analysis of high-risk predictors was described to reduce the effects of confounding and bias factors.Conclusion: The identification of MS associated with high FRS values represents a cascading of adverse effects on the population’s aging process.Keywords: aged, metabolic syndrome, cardiovascular system, aging populationGustavo de Sousa Barbalho YMorato Stival MRamos de Lima LCristina Rodrigues da Silva Ide Oliveira Silva AVieira Gomes da Costa MCristina Morais Santa Barbara Rehem TSchwerz Funghetto SDove Medical Pressarticleagedmetabolic syndromecardiovascular systemaging populationGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 15, Pp 1691-1700 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	aged metabolic syndrome cardiovascular system aging population Geriatrics RC952-954.6
spellingShingle	aged metabolic syndrome cardiovascular system aging population Geriatrics RC952-954.6 Gustavo de Sousa Barbalho Y Morato Stival M Ramos de Lima L Cristina Rodrigues da Silva I de Oliveira Silva A Vieira Gomes da Costa M Cristina Morais Santa Barbara Rehem T Schwerz Funghetto S Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults
description	Yuri Gustavo de Sousa Barbalho,1 Marina Morato Stival,1 Luciano Ramos de Lima,1 Izabel Cristina Rodrigues da Silva,1 Alessandro de Oliveira Silva,2 Manoela Vieira Gomes da Costa,1 Tania Cristina Morais Santa Barbara Rehem,1 Silvana Schwerz Funghetto1 1Graduate Department of Health Sciences and Technologies, University of Brasilia (UnB), Brasilia, Federal District, Brazil; 2Physical Education Department, University Center of Brasilia, Brasilia, Federal District, BrazilCorrespondence: Yuri Gustavo de Sousa Barbalho Tel +55 61 9 9112-7116Email yurigustavo.sousa@gmail.comObjective: Analyze the influence between the components of metabolic syndrome and the independent risk for cardiovascular disease (CVD) in the elderly.Methods: A descriptive cross-sectional study was carried out with 205 older adults from a primary healthcare unit of the Federal District, Brazil. The cardiovascular risk was determined by the Framingham Risk Score (FRS). The National Cholesterol Evaluation Program for Adult Treatment Panel III 2001 (NCEP-ATP III) criteria were considered to analyze metabolic syndrome (MS) diagnoses.Results: There was a strong association between MS and high cardiovascular risk (OR = 8.86). The univariate analysis main findings revealed that male gender, diabetes, smoking habit, systolic blood pressure, HDL level, high blood glucose, glycated hemoglobin, and LDL level were associated with high cardiovascular risk. FRS increases significantly with the presence of four or more MS components (by 30%, if 4 components are present, and by 40%, if 5 components) when compared with the presence of three or fewer components (P < 0.001). A logistic regression analysis of high-risk predictors was described to reduce the effects of confounding and bias factors.Conclusion: The identification of MS associated with high FRS values represents a cascading of adverse effects on the population’s aging process.Keywords: aged, metabolic syndrome, cardiovascular system, aging population
format	article
author	Gustavo de Sousa Barbalho Y Morato Stival M Ramos de Lima L Cristina Rodrigues da Silva I de Oliveira Silva A Vieira Gomes da Costa M Cristina Morais Santa Barbara Rehem T Schwerz Funghetto S
author_facet	Gustavo de Sousa Barbalho Y Morato Stival M Ramos de Lima L Cristina Rodrigues da Silva I de Oliveira Silva A Vieira Gomes da Costa M Cristina Morais Santa Barbara Rehem T Schwerz Funghetto S
author_sort	Gustavo de Sousa Barbalho Y
title	Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults
title_short	Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults
title_full	Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults
title_fullStr	Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults
title_full_unstemmed	Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults
title_sort	impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/8e02b62f313c443baddbbaa67c60738e
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Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults

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