Modern approaches to oxidative stress estimation, or how to measure the immeasurable

The concept of oxidative stress remains attractive to researchers combining the chemical nature of activated oxygen metabolites (AOM] and antioxidants, physical and biochemical mechanisms of action, including conditional simplicity of their versatility as redox regulators, with the original meaning...

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Autores principales:	E. B. Menshchikova, N. K. Zenkov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	antioxidants reactive oxygen species oxidative stress analysis Science Q
Acceso en línea:	https://doaj.org/article/8e090d67114d4dc09cbd00086b3ff2ef
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spelling	oai:doaj.org-article:8e090d67114d4dc09cbd00086b3ff2ef2021-11-23T06:14:34ZModern approaches to oxidative stress estimation, or how to measure the immeasurable2541-94202587-959610.12737/article_590823a565aa50.41723117https://doaj.org/article/8e090d67114d4dc09cbd00086b3ff2ef2016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/213https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The concept of oxidative stress remains attractive to researchers combining the chemical nature of activated oxygen metabolites (AOM] and antioxidants, physical and biochemical mechanisms of action, including conditional simplicity of their versatility as redox regulators, with the original meaning of the word "stress" as Selye's general adaptation syndrome. Attempts to classify the oxidative stress on the basis of its intensity and dynamics were made. The main components and driving forces of oxidative stress are pro-oxidants and antioxidants in determining that there is also a mass of inconsistencies. The main components and driving forces of oxidative stress are pro-oxidants and antioxidants in determining that there is also a mass of inconsistencies. The article discusses the basic concepts of direct relevance to the concept of oxidative stress. Existing approaches in its analysis are analyzed and it is noted that oxidative stress per se cannot be "measured". Instead, using a variety of methods, one can assess: 1] the severity and/or the stationary concentration of various types of reactive oxygen species; 2] oxidative damage of biomolecules; 3] antioxidant content/ activity, - and to apply a particular combination of parameters in order to characterize the oxidative stress intensity. The main methods, recently used for the registration of oxidative stress components, are outlined.E. B. MenshchikovaN. K. ZenkovScientific Сentre for Family Health and Human Reproduction Problemsarticleantioxidantsreactive oxygen speciesoxidative stressanalysisScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(2), Pp 174-180 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	antioxidants reactive oxygen species oxidative stress analysis Science Q
spellingShingle	antioxidants reactive oxygen species oxidative stress analysis Science Q E. B. Menshchikova N. K. Zenkov Modern approaches to oxidative stress estimation, or how to measure the immeasurable
description	The concept of oxidative stress remains attractive to researchers combining the chemical nature of activated oxygen metabolites (AOM] and antioxidants, physical and biochemical mechanisms of action, including conditional simplicity of their versatility as redox regulators, with the original meaning of the word "stress" as Selye's general adaptation syndrome. Attempts to classify the oxidative stress on the basis of its intensity and dynamics were made. The main components and driving forces of oxidative stress are pro-oxidants and antioxidants in determining that there is also a mass of inconsistencies. The main components and driving forces of oxidative stress are pro-oxidants and antioxidants in determining that there is also a mass of inconsistencies. The article discusses the basic concepts of direct relevance to the concept of oxidative stress. Existing approaches in its analysis are analyzed and it is noted that oxidative stress per se cannot be "measured". Instead, using a variety of methods, one can assess: 1] the severity and/or the stationary concentration of various types of reactive oxygen species; 2] oxidative damage of biomolecules; 3] antioxidant content/ activity, - and to apply a particular combination of parameters in order to characterize the oxidative stress intensity. The main methods, recently used for the registration of oxidative stress components, are outlined.
format	article
author	E. B. Menshchikova N. K. Zenkov
author_facet	E. B. Menshchikova N. K. Zenkov
author_sort	E. B. Menshchikova
title	Modern approaches to oxidative stress estimation, or how to measure the immeasurable
title_short	Modern approaches to oxidative stress estimation, or how to measure the immeasurable
title_full	Modern approaches to oxidative stress estimation, or how to measure the immeasurable
title_fullStr	Modern approaches to oxidative stress estimation, or how to measure the immeasurable
title_full_unstemmed	Modern approaches to oxidative stress estimation, or how to measure the immeasurable
title_sort	modern approaches to oxidative stress estimation, or how to measure the immeasurable
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/8e090d67114d4dc09cbd00086b3ff2ef
work_keys_str_mv	AT ebmenshchikova modernapproachestooxidativestressestimationorhowtomeasuretheimmeasurable AT nkzenkov modernapproachestooxidativestressestimationorhowtomeasuretheimmeasurable
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Modern approaches to oxidative stress estimation, or how to measure the immeasurable

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