Comparative Analyses of Single-Cell Transcriptomic Profiles between In Vitro Totipotent Blastomere-like Cells and In Vivo Early Mouse Embryonic Cells

Comparative Analyses of Single-Cell Transcriptomic Profiles between In Vitro Totipotent Blastomere-like Cells and In Vivo Early Mouse Embryonic Cells

The developmental potential within pluripotent cells in the canonical model is restricted to embryonic tissues, whereas totipotent cells can differentiate into both embryonic and extraembryonic tissues. Currently, the ability to culture in vitro totipotent cells possessing molecular and functional f...

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Main Authors: Po-Yu Lin, Denny Yang, Chi-Hsuan Chuang, Hsuan Lin, Wei-Ju Chen, Chia-Ying Chen, Trees-Juen Chuang, Chien-Ying Lai, Long-Yuan Li, Scott C. Schuyler, Frank Leigh Lu, Yu-Chuan Liu, Jean Lu
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
totipotency
embryonic stem cells
totipotent blastomere-like cells
2-cell-like cells (2CLCs)
spliceosome inhibitor
pladienolide B
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/8e094dcf1fb8434c986d0415f34f3a63
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https://doaj.org/article/8e094dcf1fb8434c986d0415f34f3a63

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