In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration

Extracellular matrix (ECM) is an ideal scaffold for tissue engineering but tends to lack hierarchical structure. Here the authors implant sacrificial templates subcutaneously to build an organised ECM scaffold, and following template removal and decellularisation use these scaffolds to create functi...

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Autores principales:	Meifeng Zhu, Wen Li, Xianhao Dong, Xingyu Yuan, Adam C. Midgley, Hong Chang, Yuhao Wang, Haoyu Wang, Kai Wang, Peter X. Ma, Hongjun Wang, Deling Kong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8e0c5cbb395143ea97944ec1cd4410e7
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spelling	oai:doaj.org-article:8e0c5cbb395143ea97944ec1cd4410e72021-12-02T14:38:41ZIn vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration10.1038/s41467-019-12545-32041-1723https://doaj.org/article/8e0c5cbb395143ea97944ec1cd4410e72019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12545-3https://doaj.org/toc/2041-1723Extracellular matrix (ECM) is an ideal scaffold for tissue engineering but tends to lack hierarchical structure. Here the authors implant sacrificial templates subcutaneously to build an organised ECM scaffold, and following template removal and decellularisation use these scaffolds to create functionally integrated muscle, nerve and artery in vivo.Meifeng ZhuWen LiXianhao DongXingyu YuanAdam C. MidgleyHong ChangYuhao WangHaoyu WangKai WangPeter X. MaHongjun WangDeling KongNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Meifeng Zhu Wen Li Xianhao Dong Xingyu Yuan Adam C. Midgley Hong Chang Yuhao Wang Haoyu Wang Kai Wang Peter X. Ma Hongjun Wang Deling Kong In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
description	Extracellular matrix (ECM) is an ideal scaffold for tissue engineering but tends to lack hierarchical structure. Here the authors implant sacrificial templates subcutaneously to build an organised ECM scaffold, and following template removal and decellularisation use these scaffolds to create functionally integrated muscle, nerve and artery in vivo.
format	article
author	Meifeng Zhu Wen Li Xianhao Dong Xingyu Yuan Adam C. Midgley Hong Chang Yuhao Wang Haoyu Wang Kai Wang Peter X. Ma Hongjun Wang Deling Kong
author_facet	Meifeng Zhu Wen Li Xianhao Dong Xingyu Yuan Adam C. Midgley Hong Chang Yuhao Wang Haoyu Wang Kai Wang Peter X. Ma Hongjun Wang Deling Kong
author_sort	Meifeng Zhu
title	In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
title_short	In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
title_full	In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
title_fullStr	In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
title_full_unstemmed	In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
title_sort	in vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8e0c5cbb395143ea97944ec1cd4410e7
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In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration

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