Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of <i>Vibrio cholerae</i> O-Specific Polysaccharide-Specific Monoclonal Antibodies

Immunity to the severe diarrheal disease cholera is largely mediated by lipopolysaccharide (LPS)-specific antibodies. However, the properties and protective mechanism of functionally relevant antibodies have not been well defined.

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Detalles Bibliográficos
Autores principales: Robert C. Kauffman, Oluwaseyi Adekunle, Hanyi Yu, Alice Cho, Lindsay E. Nyhoff, Meagan Kelly, Jason B. Harris, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Stephen B. Calderwood, Richelle C. Charles, Edward T. Ryan, Jun Kong, Jens Wrammert
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/8e0f934dff5f485db6acca027300e978
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Descripción
Sumario:Immunity to the severe diarrheal disease cholera is largely mediated by lipopolysaccharide (LPS)-specific antibodies. However, the properties and protective mechanism of functionally relevant antibodies have not been well defined.