Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of <i>Vibrio cholerae</i> O-Specific Polysaccharide-Specific Monoclonal Antibodies
Immunity to the severe diarrheal disease cholera is largely mediated by lipopolysaccharide (LPS)-specific antibodies. However, the properties and protective mechanism of functionally relevant antibodies have not been well defined.
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American Society for Microbiology
2021
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oai:doaj.org-article:8e0f934dff5f485db6acca027300e9782021-11-03T18:56:10Z Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of <i>Vibrio cholerae</i> O-Specific Polysaccharide-Specific Monoclonal Antibodies 2150-751110.1128/mBio.03679-20https://doaj.org/article/8e0f934dff5f485db6acca027300e9782021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03679-20https://doaj.org/toc/2150-7511 Immunity to the severe diarrheal disease cholera is largely mediated by lipopolysaccharide (LPS)-specific antibodies. However, the properties and protective mechanism of functionally relevant antibodies have not been well defined.Robert C. KauffmanOluwaseyi AdekunleHanyi YuAlice ChoLindsay E. NyhoffMeagan KellyJason B. HarrisTaufiqur Rahman BhuiyanFirdausi QadriStephen B. CalderwoodRichelle C. CharlesEdward T. RyanJun KongJens WrammertAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Robert C. Kauffman Oluwaseyi Adekunle Hanyi Yu Alice Cho Lindsay E. Nyhoff Meagan Kelly Jason B. Harris Taufiqur Rahman Bhuiyan Firdausi Qadri Stephen B. Calderwood Richelle C. Charles Edward T. Ryan Jun Kong Jens Wrammert Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of <i>Vibrio cholerae</i> O-Specific Polysaccharide-Specific Monoclonal Antibodies |
| description |
Immunity to the severe diarrheal disease cholera is largely mediated by lipopolysaccharide (LPS)-specific antibodies. However, the properties and protective mechanism of functionally relevant antibodies have not been well defined. |
| format |
article |
| author |
Robert C. Kauffman Oluwaseyi Adekunle Hanyi Yu Alice Cho Lindsay E. Nyhoff Meagan Kelly Jason B. Harris Taufiqur Rahman Bhuiyan Firdausi Qadri Stephen B. Calderwood Richelle C. Charles Edward T. Ryan Jun Kong Jens Wrammert |
| author_facet |
Robert C. Kauffman Oluwaseyi Adekunle Hanyi Yu Alice Cho Lindsay E. Nyhoff Meagan Kelly Jason B. Harris Taufiqur Rahman Bhuiyan Firdausi Qadri Stephen B. Calderwood Richelle C. Charles Edward T. Ryan Jun Kong Jens Wrammert |
| author_sort |
Robert C. Kauffman |
| title |
Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of
<i>Vibrio cholerae</i>
O-Specific Polysaccharide-Specific Monoclonal Antibodies
|
| title_short |
Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of
<i>Vibrio cholerae</i>
O-Specific Polysaccharide-Specific Monoclonal Antibodies
|
| title_full |
Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of
<i>Vibrio cholerae</i>
O-Specific Polysaccharide-Specific Monoclonal Antibodies
|
| title_fullStr |
Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of
<i>Vibrio cholerae</i>
O-Specific Polysaccharide-Specific Monoclonal Antibodies
|
| title_full_unstemmed |
Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of
<i>Vibrio cholerae</i>
O-Specific Polysaccharide-Specific Monoclonal Antibodies
|
| title_sort |
impact of immunoglobulin isotype and epitope on the functional properties of
<i>vibrio cholerae</i>
o-specific polysaccharide-specific monoclonal antibodies |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/8e0f934dff5f485db6acca027300e978 |
| work_keys_str_mv |
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| _version_ |
1718445468378202112 |