Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia

Feng-Juan Hu,1,2 Hu Liu,3 Xiao-Lei Liu,1,2 Shu-Li Jia,1,2 Li-Sha Hou,2 Xin Xia,2 Bi-Rong Dong1,2 1Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2National Clinical Research Center of Geriatrics, West China Hospit...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hu FJ, Liu H, Liu XL, Jia SL, Hou LS, Xia X, Dong BR
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	anthropometry low muscle mass diagnosis older adults Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/8e17c5b8db484a8cbb55300c45edea46
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8e17c5b8db484a8cbb55300c45edea46
record_format	dspace
spelling	oai:doaj.org-article:8e17c5b8db484a8cbb55300c45edea462021-12-02T17:40:54ZMid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia1178-1998https://doaj.org/article/8e17c5b8db484a8cbb55300c45edea462021-06-01T00:00:00Zhttps://www.dovepress.com/mid-upper-arm-circumference-as-an-alternative-screening-instrument-to--peer-reviewed-fulltext-article-CIAhttps://doaj.org/toc/1178-1998Feng-Juan Hu,1,2 Hu Liu,3 Xiao-Lei Liu,1,2 Shu-Li Jia,1,2 Li-Sha Hou,2 Xin Xia,2 Bi-Rong Dong1,2 1Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2National Clinical Research Center of Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 3Department of Liver Surgery, Liver Transplantation Division, Laboratory of Liver Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Bi-Rong DongCenter of Gerontology and Geriatrics, West China Hospital, Sichuan University, GuoXueXiang 37, Chengdu, Sichuan, 610041, People’s Republic of ChinaTel +86-28-85421550Fax +86-28-85421550Email birongdong123@outlook.comPurpose: Mid-upper arm circumference (MUAC) is a simple, noninvasive anthropometric indicator. This study evaluated the applicability of MUAC as an alternative screening instrument to appendicular skeletal muscle mass index (ASMI) for detecting sarcopenia, and determined the optimal MUAC cutoff values.Patients and Methods: A total of 4509 subjects ≥ 50 years of age from the West China Health and Aging Trend study were included in the present study. ASM was measured by bioelectrical impedance analysis. MUAC, calf circumference (CC), and grip strength were evaluated and the Short Physical Performance Battery and 3-m timed up-and-go test were administered. Low muscle mass was diagnosed based on Asian Working Group for Sarcopenia 2019 (AWGS2019) and updated European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria.Results: ASMI was positively correlated with MUAC in both men (r=0.726, P< 0.001) and women (r=0.698, P< 0.001). The area under the receiver operating characteristic curve (AUC) for MUAC as an indicator of low muscle mass in men and women was 0.86 (95% confidence interval [CI]: 0.85– 0.88) and 0.85 (95% CI: 0.84– 0.86), respectively, according to AWGS2019 criteria; and 0.86 (95% CI: 0.85– 0.88) and 0.86 (95% CI: 0.85– 0.88), respectively, according to EWGSOP2 criteria. Optimal MUAC cutoff values for predicting low muscle mass were ≤ 28.6 cm for men and ≤ 27.5 cm for women. There was no significant difference between the AUCs of MUAC and CC in men according to the 2 reference standards (P=0.809), whereas the AUC of CC was superior to that of MUAC in women according to AWGS2019 (P< 0.001) and EWGSOP2 (P=0.008) criteria.Conclusion: MUAC is strongly correlated with ASMI among community-dwelling middle-aged and older adults in China. MUAC can be used as a simple screening instrument to ASMI for diagnosing sarcopenia, especially in men.Keywords: anthropometry, low muscle mass, diagnosis, older adultsHu FJLiu HLiu XLJia SLHou LSXia XDong BRDove Medical Pressarticleanthropometrylow muscle massdiagnosisolder adultsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 16, Pp 1095-1104 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	anthropometry low muscle mass diagnosis older adults Geriatrics RC952-954.6
spellingShingle	anthropometry low muscle mass diagnosis older adults Geriatrics RC952-954.6 Hu FJ Liu H Liu XL Jia SL Hou LS Xia X Dong BR Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
description	Feng-Juan Hu,1,2 Hu Liu,3 Xiao-Lei Liu,1,2 Shu-Li Jia,1,2 Li-Sha Hou,2 Xin Xia,2 Bi-Rong Dong1,2 1Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2National Clinical Research Center of Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 3Department of Liver Surgery, Liver Transplantation Division, Laboratory of Liver Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Bi-Rong DongCenter of Gerontology and Geriatrics, West China Hospital, Sichuan University, GuoXueXiang 37, Chengdu, Sichuan, 610041, People’s Republic of ChinaTel +86-28-85421550Fax +86-28-85421550Email birongdong123@outlook.comPurpose: Mid-upper arm circumference (MUAC) is a simple, noninvasive anthropometric indicator. This study evaluated the applicability of MUAC as an alternative screening instrument to appendicular skeletal muscle mass index (ASMI) for detecting sarcopenia, and determined the optimal MUAC cutoff values.Patients and Methods: A total of 4509 subjects ≥ 50 years of age from the West China Health and Aging Trend study were included in the present study. ASM was measured by bioelectrical impedance analysis. MUAC, calf circumference (CC), and grip strength were evaluated and the Short Physical Performance Battery and 3-m timed up-and-go test were administered. Low muscle mass was diagnosed based on Asian Working Group for Sarcopenia 2019 (AWGS2019) and updated European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria.Results: ASMI was positively correlated with MUAC in both men (r=0.726, P< 0.001) and women (r=0.698, P< 0.001). The area under the receiver operating characteristic curve (AUC) for MUAC as an indicator of low muscle mass in men and women was 0.86 (95% confidence interval [CI]: 0.85– 0.88) and 0.85 (95% CI: 0.84– 0.86), respectively, according to AWGS2019 criteria; and 0.86 (95% CI: 0.85– 0.88) and 0.86 (95% CI: 0.85– 0.88), respectively, according to EWGSOP2 criteria. Optimal MUAC cutoff values for predicting low muscle mass were ≤ 28.6 cm for men and ≤ 27.5 cm for women. There was no significant difference between the AUCs of MUAC and CC in men according to the 2 reference standards (P=0.809), whereas the AUC of CC was superior to that of MUAC in women according to AWGS2019 (P< 0.001) and EWGSOP2 (P=0.008) criteria.Conclusion: MUAC is strongly correlated with ASMI among community-dwelling middle-aged and older adults in China. MUAC can be used as a simple screening instrument to ASMI for diagnosing sarcopenia, especially in men.Keywords: anthropometry, low muscle mass, diagnosis, older adults
format	article
author	Hu FJ Liu H Liu XL Jia SL Hou LS Xia X Dong BR
author_facet	Hu FJ Liu H Liu XL Jia SL Hou LS Xia X Dong BR
author_sort	Hu FJ
title	Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_short	Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_full	Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_fullStr	Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_full_unstemmed	Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_sort	mid-upper arm circumference as an alternative screening instrument to appendicular skeletal muscle mass index for diagnosing sarcopenia
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/8e17c5b8db484a8cbb55300c45edea46
work_keys_str_mv	AT hufj midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia AT liuh midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia AT liuxl midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia AT jiasl midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia AT houls midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia AT xiax midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia AT dongbr midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia
_version_	1718379716695556096

Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia

Ejemplares similares