Prohibitins are required for cancer cell proliferation and adhesion.
Prohibitin 1 (PHB1) is a highly conserved protein that together with its homologue prohibitin 2 (PHB2) mainly localizes to the inner mitochondrial membrane. Although it was originally identified by its ability to inhibit G1/S progression in human fibroblasts, its role as tumor suppressor is debated....
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Autores principales: | Claudia Sievers, Gwendolyn Billig, Kathleen Gottschalk, Thomas Rudel |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/8e211fe834d7407d879d102cb32c8877 |
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