Possible sertraline-induced extrapyramidal adverse effects in an adolescent

Lian-fang Wang,1 Jin-wen Huang,1 Si-yang Shan,2 Jia-hong Ding,3 Jian-bo Lai,1,2 Yi Xu,1,4 Shao-hua Hu1,4 1Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, 2Faculty of Clinical Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, Peopl...

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Autores principales:	Wang LF, Huang JW, Shan SY, Ding JH, Lai JB, Xu Y, Hu SH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	adolescents selective serotonin reuptake inhibitors sertraline extrapyramidal symptoms Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/8e2394d4c2d74ed592bbcc5c6ed8eea2
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spelling	oai:doaj.org-article:8e2394d4c2d74ed592bbcc5c6ed8eea22021-12-02T03:24:15ZPossible sertraline-induced extrapyramidal adverse effects in an adolescent1178-2021https://doaj.org/article/8e2394d4c2d74ed592bbcc5c6ed8eea22016-05-01T00:00:00Zhttps://www.dovepress.com/possible-sertraline-induced-extrapyramidal-adverse-effects-in-an-adole-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Lian-fang Wang,1 Jin-wen Huang,1 Si-yang Shan,2 Jia-hong Ding,3 Jian-bo Lai,1,2 Yi Xu,1,4 Shao-hua Hu1,4 1Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, 2Faculty of Clinical Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 3Department of Psychology, University of Hong Kong, Pokfulam, Hong Kong; 4The Key Laboratory of Mental Disorder’s Management in Zhejiang Province, National Clinical Research Center for Mental Health Disorders, Hangzhou, Zhejiang, People’s Republic of China Abstract: Sertraline has been considered to be a relatively safe selective serotonin reuptake inhibitor for adolescents for a long time. We report herein a case of a 16-year-old Chinese boy with depression who experienced extrapyramidal-like effects, for example, facial spasm, upper limb dystonia, akathisia, and other disturbed behaviors, while being treated with sertraline 200 mg per day. His movement symptoms were significantly alleviated after the discontinuation of sertraline and the administration of scopolamine. This finding indicates that albeit infrequent, sertraline may cause severe extrapyramidal symptoms in adolescent patients, suggesting that clinicians should be alert to the neurological side effects of sertraline in young patients. Keywords: adolescents, selective serotonin reuptake inhibitors, sertraline, extrapyramidal symptomsWang LFHuang JWShan SYDing JHLai JBXu YHu SHDove Medical Pressarticleadolescentsselective serotonin reuptake inhibitorssertralineextrapyramidal symptomsNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 1127-1129 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	adolescents selective serotonin reuptake inhibitors sertraline extrapyramidal symptoms Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	adolescents selective serotonin reuptake inhibitors sertraline extrapyramidal symptoms Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Wang LF Huang JW Shan SY Ding JH Lai JB Xu Y Hu SH Possible sertraline-induced extrapyramidal adverse effects in an adolescent
description	Lian-fang Wang,1 Jin-wen Huang,1 Si-yang Shan,2 Jia-hong Ding,3 Jian-bo Lai,1,2 Yi Xu,1,4 Shao-hua Hu1,4 1Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, 2Faculty of Clinical Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 3Department of Psychology, University of Hong Kong, Pokfulam, Hong Kong; 4The Key Laboratory of Mental Disorder’s Management in Zhejiang Province, National Clinical Research Center for Mental Health Disorders, Hangzhou, Zhejiang, People’s Republic of China Abstract: Sertraline has been considered to be a relatively safe selective serotonin reuptake inhibitor for adolescents for a long time. We report herein a case of a 16-year-old Chinese boy with depression who experienced extrapyramidal-like effects, for example, facial spasm, upper limb dystonia, akathisia, and other disturbed behaviors, while being treated with sertraline 200 mg per day. His movement symptoms were significantly alleviated after the discontinuation of sertraline and the administration of scopolamine. This finding indicates that albeit infrequent, sertraline may cause severe extrapyramidal symptoms in adolescent patients, suggesting that clinicians should be alert to the neurological side effects of sertraline in young patients. Keywords: adolescents, selective serotonin reuptake inhibitors, sertraline, extrapyramidal symptoms
format	article
author	Wang LF Huang JW Shan SY Ding JH Lai JB Xu Y Hu SH
author_facet	Wang LF Huang JW Shan SY Ding JH Lai JB Xu Y Hu SH
author_sort	Wang LF
title	Possible sertraline-induced extrapyramidal adverse effects in an adolescent
title_short	Possible sertraline-induced extrapyramidal adverse effects in an adolescent
title_full	Possible sertraline-induced extrapyramidal adverse effects in an adolescent
title_fullStr	Possible sertraline-induced extrapyramidal adverse effects in an adolescent
title_full_unstemmed	Possible sertraline-induced extrapyramidal adverse effects in an adolescent
title_sort	possible sertraline-induced extrapyramidal adverse effects in an adolescent
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/8e2394d4c2d74ed592bbcc5c6ed8eea2
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Possible sertraline-induced extrapyramidal adverse effects in an adolescent

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