Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

Understanding the genetic influences on human aging requires a large number of subjects for a study of sufficient power. Here, Jim Wilson and colleagues use information on parental ages at death to show that common variants near the genes for apolipoprotein E and nicotinic acetylcholine receptor sub...

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Autores principales:	Peter K. Joshi, Krista Fischer, Katharina E. Schraut, Harry Campbell, Tõnu Esko, James F. Wilson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8e27ea7a9faf4fdf809be7c157f8f6a1
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spelling	oai:doaj.org-article:8e27ea7a9faf4fdf809be7c157f8f6a12021-12-02T14:39:16ZVariants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan10.1038/ncomms111742041-1723https://doaj.org/article/8e27ea7a9faf4fdf809be7c157f8f6a12016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11174https://doaj.org/toc/2041-1723Understanding the genetic influences on human aging requires a large number of subjects for a study of sufficient power. Here, Jim Wilson and colleagues use information on parental ages at death to show that common variants near the genes for apolipoprotein E and nicotinic acetylcholine receptor subunit alpha 5 are associated with longer lifespan.Peter K. JoshiKrista FischerKatharina E. SchrautHarry CampbellTõnu EskoJames F. WilsonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peter K. Joshi Krista Fischer Katharina E. Schraut Harry Campbell Tõnu Esko James F. Wilson Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan
description	Understanding the genetic influences on human aging requires a large number of subjects for a study of sufficient power. Here, Jim Wilson and colleagues use information on parental ages at death to show that common variants near the genes for apolipoprotein E and nicotinic acetylcholine receptor subunit alpha 5 are associated with longer lifespan.
format	article
author	Peter K. Joshi Krista Fischer Katharina E. Schraut Harry Campbell Tõnu Esko James F. Wilson
author_facet	Peter K. Joshi Krista Fischer Katharina E. Schraut Harry Campbell Tõnu Esko James F. Wilson
author_sort	Peter K. Joshi
title	Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan
title_short	Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan
title_full	Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan
title_fullStr	Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan
title_full_unstemmed	Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan
title_sort	variants near chrna3/5 and apoe have age- and sex-related effects on human lifespan
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8e27ea7a9faf4fdf809be7c157f8f6a1
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Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

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