Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease

Background: The diagnosis of chronic kidney disease (CKD) is usually delayed, when significant functional renal impairment has already occurred. The diagnosis is complex and clinical and laboratory investigations play a crucial role. There are well-established markers of CKD – serum creatinine and c...

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Autores principales: Genov D., Kundurdgiev A., Ivanova I., Nikolova M., Pencheva V., Hristova M., Koleva N., Kostadinova A., Vutova Ts.
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Lenguaje:EN
Publicado: Sciendo 2021
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Acceso en línea:https://doaj.org/article/8e41e10b63af4bd8a8509f0c05420fb9
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spelling oai:doaj.org-article:8e41e10b63af4bd8a8509f0c05420fb92021-12-02T19:11:31ZRole of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease0324-175010.2478/amb-2021-0002https://doaj.org/article/8e41e10b63af4bd8a8509f0c05420fb92021-04-01T00:00:00Zhttps://doi.org/10.2478/amb-2021-0002https://doaj.org/toc/0324-1750Background: The diagnosis of chronic kidney disease (CKD) is usually delayed, when significant functional renal impairment has already occurred. The diagnosis is complex and clinical and laboratory investigations play a crucial role. There are well-established markers of CKD – serum creatinine and cystatin C. However, the search for new reliable biomarkers that aid in the assessment of kidney function and predict the evolution of the disease is still in progress.Genov D.Kundurdgiev A.Ivanova I.Nikolova M.Pencheva V.Hristova M.Koleva N.Kostadinova A.Vutova Ts.Sciendoarticleserum uromodulinchronic kidney diseasebiomarkerserum creatininecystatin cMedicineRENActa Medica Bulgarica, Vol 48, Iss 1, Pp 13-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic serum uromodulin
chronic kidney disease
biomarker
serum creatinine
cystatin c
Medicine
R
spellingShingle serum uromodulin
chronic kidney disease
biomarker
serum creatinine
cystatin c
Medicine
R
Genov D.
Kundurdgiev A.
Ivanova I.
Nikolova M.
Pencheva V.
Hristova M.
Koleva N.
Kostadinova A.
Vutova Ts.
Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease
description Background: The diagnosis of chronic kidney disease (CKD) is usually delayed, when significant functional renal impairment has already occurred. The diagnosis is complex and clinical and laboratory investigations play a crucial role. There are well-established markers of CKD – serum creatinine and cystatin C. However, the search for new reliable biomarkers that aid in the assessment of kidney function and predict the evolution of the disease is still in progress.
format article
author Genov D.
Kundurdgiev A.
Ivanova I.
Nikolova M.
Pencheva V.
Hristova M.
Koleva N.
Kostadinova A.
Vutova Ts.
author_facet Genov D.
Kundurdgiev A.
Ivanova I.
Nikolova M.
Pencheva V.
Hristova M.
Koleva N.
Kostadinova A.
Vutova Ts.
author_sort Genov D.
title Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease
title_short Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease
title_full Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease
title_fullStr Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease
title_full_unstemmed Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease
title_sort role of serum uromodulin in the early diagnosis of chronic kidney disease
publisher Sciendo
publishDate 2021
url https://doaj.org/article/8e41e10b63af4bd8a8509f0c05420fb9
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