Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease
Background: The diagnosis of chronic kidney disease (CKD) is usually delayed, when significant functional renal impairment has already occurred. The diagnosis is complex and clinical and laboratory investigations play a crucial role. There are well-established markers of CKD – serum creatinine and c...
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2021
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oai:doaj.org-article:8e41e10b63af4bd8a8509f0c05420fb92021-12-02T19:11:31ZRole of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease0324-175010.2478/amb-2021-0002https://doaj.org/article/8e41e10b63af4bd8a8509f0c05420fb92021-04-01T00:00:00Zhttps://doi.org/10.2478/amb-2021-0002https://doaj.org/toc/0324-1750Background: The diagnosis of chronic kidney disease (CKD) is usually delayed, when significant functional renal impairment has already occurred. The diagnosis is complex and clinical and laboratory investigations play a crucial role. There are well-established markers of CKD – serum creatinine and cystatin C. However, the search for new reliable biomarkers that aid in the assessment of kidney function and predict the evolution of the disease is still in progress.Genov D.Kundurdgiev A.Ivanova I.Nikolova M.Pencheva V.Hristova M.Koleva N.Kostadinova A.Vutova Ts.Sciendoarticleserum uromodulinchronic kidney diseasebiomarkerserum creatininecystatin cMedicineRENActa Medica Bulgarica, Vol 48, Iss 1, Pp 13-16 (2021) |
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serum uromodulin chronic kidney disease biomarker serum creatinine cystatin c Medicine R |
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serum uromodulin chronic kidney disease biomarker serum creatinine cystatin c Medicine R Genov D. Kundurdgiev A. Ivanova I. Nikolova M. Pencheva V. Hristova M. Koleva N. Kostadinova A. Vutova Ts. Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease |
description |
Background: The diagnosis of chronic kidney disease (CKD) is usually delayed, when significant functional renal impairment has already occurred. The diagnosis is complex and clinical and laboratory investigations play a crucial role. There are well-established markers of CKD – serum creatinine and cystatin C. However, the search for new reliable biomarkers that aid in the assessment of kidney function and predict the evolution of the disease is still in progress. |
format |
article |
author |
Genov D. Kundurdgiev A. Ivanova I. Nikolova M. Pencheva V. Hristova M. Koleva N. Kostadinova A. Vutova Ts. |
author_facet |
Genov D. Kundurdgiev A. Ivanova I. Nikolova M. Pencheva V. Hristova M. Koleva N. Kostadinova A. Vutova Ts. |
author_sort |
Genov D. |
title |
Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease |
title_short |
Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease |
title_full |
Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease |
title_fullStr |
Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease |
title_full_unstemmed |
Role of Serum Uromodulin in the Early Diagnosis of Chronic Kidney Disease |
title_sort |
role of serum uromodulin in the early diagnosis of chronic kidney disease |
publisher |
Sciendo |
publishDate |
2021 |
url |
https://doaj.org/article/8e41e10b63af4bd8a8509f0c05420fb9 |
work_keys_str_mv |
AT genovd roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT kundurdgieva roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT ivanovai roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT nikolovam roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT penchevav roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT hristovam roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT kolevan roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT kostadinovaa roleofserumuromodulinintheearlydiagnosisofchronickidneydisease AT vutovats roleofserumuromodulinintheearlydiagnosisofchronickidneydisease |
_version_ |
1718377101385531392 |