A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP

Abstract Extensive functional studies of the exchange protein directly activated by cAMP (EPAC) family of signaling molecules have demonstrated that EPAC proteins play a fundamental role in several physiological and pathophysiological responses, therefore are attractive drug targets. In this report,...

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Autores principales: Yingmin Zhu, Fang Mei, Pei Luo, Xiaodong Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8e4267e28d4147aeaf640b336e562918
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