Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice

Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice

Tzong-Shiue Yu et al. assess the impact of astrocytic ApoE on hippocampal neurogenesis and behavior after traumatic brain injury (TBI) in mice. Their results suggest that postnatal ablation of astrocytic APOE reduces dendritic complexity in newborn dentate gyrus neurons and cognitive ability, provid...

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Autores principales: Tzong-Shiue Yu, Yacine Tensaouti, Elizabeth P. Stephanz, Sana Chintamen, Elizabeth E. Rafikian, Mu Yang, Steven G. Kernie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/8e490df72bc349c28fdbc9e8ef79a769
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