Transoral flexible laryngoscope biopsy: Safety and accuracy

Objective: To determine the accuracy of transoral flexible laryngoscope (TFL) biopsy and also to identify the safety as office based procedure in terms of complications. Methods: This is a diagnostic study; the type of intervention is outpatient department based biopsy of laryngeal lesions. All pati...

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Autores principales:	Nabeel Humayun Hassan, Rahila Usman, Muhammad Yousuf, Ahmad Nawaz Ahmad, Ismail Hirani
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2019
Materias:	Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/8e53e3994ca344dc8401042b946cd0cf
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spelling	oai:doaj.org-article:8e53e3994ca344dc8401042b946cd0cf2021-12-02T13:45:19ZTransoral flexible laryngoscope biopsy: Safety and accuracy2095-881110.1016/j.wjorl.2018.09.003https://doaj.org/article/8e53e3994ca344dc8401042b946cd0cf2019-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881117300987https://doaj.org/toc/2095-8811Objective: To determine the accuracy of transoral flexible laryngoscope (TFL) biopsy and also to identify the safety as office based procedure in terms of complications. Methods: This is a diagnostic study; the type of intervention is outpatient department based biopsy of laryngeal lesions. All patients seen in ENT outpatient department of Lyari General Hospital with suspicious lesions of Larynx were referred for Transoral Flexible Laryngoscopy Biopsy under local anesthesia. The specimens were sent for histopathology. The patients with benign pathology or carcinoma in situ were referred for direct laryngoscopy and biopsy. The sensitivity and specificity were calculated and the frequencies of complications were monitored to determine the complication rate. Results: During the course of study a total of 47 patients underwent TFL biopsy in office settings. Out of these patients 16 patients were referred for direct laryngoscopy biopsy. The study population included 32 men and 15 women with ages ranging from 28 to 52 years and mean of (39 ± 6) years. Among 43 patients squamous cell carcinoma was the final diagnosis in 31 patients. In the rest of 12 patients’ dysplasia and benign lesion was the diagnosis in 9 and 3 patients respectively. These 12 patients underwent direct laryngoscopy biopsy and 10 of them diagnosed with invasive carcinoma rest had benign lesions. Hence the specificity was 75.6% and sensitivity was 100%. None of the patients developed any serious complication. Conclusions: All patients with a suspicious lesion diagnosed by TFL biopsy as being benign or carcinoma in situ should have direct laryngoscopy for verification of the findings. But the results positive for carcinoma are reliable. In addition, this is a safe procedure. Keywords: Biopsy, Flexible laryngoscopy, Squamous cell carcinoma, LarynxNabeel Humayun HassanRahila UsmanMuhammad YousufAhmad Nawaz AhmadIsmail HiraniKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 5, Iss 1, Pp 30-33 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Otorhinolaryngology RF1-547 Surgery RD1-811 Nabeel Humayun Hassan Rahila Usman Muhammad Yousuf Ahmad Nawaz Ahmad Ismail Hirani Transoral flexible laryngoscope biopsy: Safety and accuracy
description	Objective: To determine the accuracy of transoral flexible laryngoscope (TFL) biopsy and also to identify the safety as office based procedure in terms of complications. Methods: This is a diagnostic study; the type of intervention is outpatient department based biopsy of laryngeal lesions. All patients seen in ENT outpatient department of Lyari General Hospital with suspicious lesions of Larynx were referred for Transoral Flexible Laryngoscopy Biopsy under local anesthesia. The specimens were sent for histopathology. The patients with benign pathology or carcinoma in situ were referred for direct laryngoscopy and biopsy. The sensitivity and specificity were calculated and the frequencies of complications were monitored to determine the complication rate. Results: During the course of study a total of 47 patients underwent TFL biopsy in office settings. Out of these patients 16 patients were referred for direct laryngoscopy biopsy. The study population included 32 men and 15 women with ages ranging from 28 to 52 years and mean of (39 ± 6) years. Among 43 patients squamous cell carcinoma was the final diagnosis in 31 patients. In the rest of 12 patients’ dysplasia and benign lesion was the diagnosis in 9 and 3 patients respectively. These 12 patients underwent direct laryngoscopy biopsy and 10 of them diagnosed with invasive carcinoma rest had benign lesions. Hence the specificity was 75.6% and sensitivity was 100%. None of the patients developed any serious complication. Conclusions: All patients with a suspicious lesion diagnosed by TFL biopsy as being benign or carcinoma in situ should have direct laryngoscopy for verification of the findings. But the results positive for carcinoma are reliable. In addition, this is a safe procedure. Keywords: Biopsy, Flexible laryngoscopy, Squamous cell carcinoma, Larynx
format	article
author	Nabeel Humayun Hassan Rahila Usman Muhammad Yousuf Ahmad Nawaz Ahmad Ismail Hirani
author_facet	Nabeel Humayun Hassan Rahila Usman Muhammad Yousuf Ahmad Nawaz Ahmad Ismail Hirani
author_sort	Nabeel Humayun Hassan
title	Transoral flexible laryngoscope biopsy: Safety and accuracy
title_short	Transoral flexible laryngoscope biopsy: Safety and accuracy
title_full	Transoral flexible laryngoscope biopsy: Safety and accuracy
title_fullStr	Transoral flexible laryngoscope biopsy: Safety and accuracy
title_full_unstemmed	Transoral flexible laryngoscope biopsy: Safety and accuracy
title_sort	transoral flexible laryngoscope biopsy: safety and accuracy
publisher	KeAi Communications Co., Ltd.
publishDate	2019
url	https://doaj.org/article/8e53e3994ca344dc8401042b946cd0cf
work_keys_str_mv	AT nabeelhumayunhassan transoralflexiblelaryngoscopebiopsysafetyandaccuracy AT rahilausman transoralflexiblelaryngoscopebiopsysafetyandaccuracy AT muhammadyousuf transoralflexiblelaryngoscopebiopsysafetyandaccuracy AT ahmadnawazahmad transoralflexiblelaryngoscopebiopsysafetyandaccuracy AT ismailhirani transoralflexiblelaryngoscopebiopsysafetyandaccuracy
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Transoral flexible laryngoscope biopsy: Safety and accuracy

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