The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health
Kelvin Li,1,* Xia-Fang Wang,2,3,* Ding-You Li,4 Yuan-Cheng Chen,2 Lan-Juan Zhao,1 Xiao-Gang Liu,5 Yan-Fang Guo,6 Jie Shen,2 Xu Lin,2 Jeffrey Deng,1 Rou Zhou,2 Hong-Wen Deng1,7 1Center for Bioinformatics and Genomics, Department of Global Biostatistics and Data Science, Tulane University, New Orlean...
Guardado en:
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2018
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/8e5ba74416814ff7b6375a678dbd2993 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:8e5ba74416814ff7b6375a678dbd2993 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:8e5ba74416814ff7b6375a678dbd29932021-12-02T04:53:55ZThe good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health1178-1998https://doaj.org/article/8e5ba74416814ff7b6375a678dbd29932018-11-01T00:00:00Zhttps://www.dovepress.com/the-good-the-bad-and-the-ugly-of-calcium-supplementation-a-review-of-c-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Kelvin Li,1,* Xia-Fang Wang,2,3,* Ding-You Li,4 Yuan-Cheng Chen,2 Lan-Juan Zhao,1 Xiao-Gang Liu,5 Yan-Fang Guo,6 Jie Shen,2 Xu Lin,2 Jeffrey Deng,1 Rou Zhou,2 Hong-Wen Deng1,7 1Center for Bioinformatics and Genomics, Department of Global Biostatistics and Data Science, Tulane University, New Orleans, LA 70112, USA; 2Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong 510630, People’s Republic of China; 3Department of Endocrinology and Metabolism, Hengyang Central Hospital, Hengyang, Hunan 421000, People’s Republic of China; 4Department of Gastroenterology, Children’s Mercy Kansas City, University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA; 5School of Life Science and Technology, Xi’an Jiao Tong University, Xi’an, Shanxi 710049, People’s Republic of China; 6Institute of Bioinformatics, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong 510515, People’s Republic of China; 7School of Basic Medical Science, National Clinical Research Center for Geriatric Diseases, Xiangya Hospital, Central South University, Changsha, Hunan 410078, People’s Republic of China *These authors contributed equally to this work Abstract: Calcium is an important integrative component of the human body and critical for human health. It has been well established that calcium intake is helpful in the prevention and treatment of osteoporosis, which has become one of the most serious public health problems across the world. However, community-dwelling adults with and without osteoporosis are rarely concerned or even not aware of the potential side effects of high or inappropriate doses of calcium intake. Some recent studies have revealed that excessive calcium intake might increase the risks of cardiovascular diseases. The purpose of this article was to review the health benefits, costs, and consequences of calcium supplementation on osteoporosis/osteoporotic fractures, cardiovascular events, kidney stones, gastrointestinal diseases, and other important diseases. In the end, we suggest that calcium supplementation should be prescribed and taken cautiously, accounting for individual patients’ risks and benefits. Clearly, further studies are needed to examine the health effects of calcium supplementation to make any solid recommendations for people of different genders, ages, and ethnicities. Keywords: calcium, osteoporosis, osteoporotic fractures, cardiovascular diseases, kidney stones, gastrointestinal diseasesLi KWang XFLi DYChen YCZhao LJLiu XGGuo YFShen JLin XDeng JZhou RDeng HWDove Medical Pressarticlecalcium supplementationosteoporosisosteoporotic fracturescardiovascular diseaseskidney stonesgastrointestinal diseasesGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 13, Pp 2443-2452 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
calcium supplementation osteoporosis osteoporotic fractures cardiovascular diseases kidney stones gastrointestinal diseases Geriatrics RC952-954.6 |
| spellingShingle |
calcium supplementation osteoporosis osteoporotic fractures cardiovascular diseases kidney stones gastrointestinal diseases Geriatrics RC952-954.6 Li K Wang XF Li DY Chen YC Zhao LJ Liu XG Guo YF Shen J Lin X Deng J Zhou R Deng HW The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health |
| description |
Kelvin Li,1,* Xia-Fang Wang,2,3,* Ding-You Li,4 Yuan-Cheng Chen,2 Lan-Juan Zhao,1 Xiao-Gang Liu,5 Yan-Fang Guo,6 Jie Shen,2 Xu Lin,2 Jeffrey Deng,1 Rou Zhou,2 Hong-Wen Deng1,7 1Center for Bioinformatics and Genomics, Department of Global Biostatistics and Data Science, Tulane University, New Orleans, LA 70112, USA; 2Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong 510630, People’s Republic of China; 3Department of Endocrinology and Metabolism, Hengyang Central Hospital, Hengyang, Hunan 421000, People’s Republic of China; 4Department of Gastroenterology, Children’s Mercy Kansas City, University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA; 5School of Life Science and Technology, Xi’an Jiao Tong University, Xi’an, Shanxi 710049, People’s Republic of China; 6Institute of Bioinformatics, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong 510515, People’s Republic of China; 7School of Basic Medical Science, National Clinical Research Center for Geriatric Diseases, Xiangya Hospital, Central South University, Changsha, Hunan 410078, People’s Republic of China *These authors contributed equally to this work Abstract: Calcium is an important integrative component of the human body and critical for human health. It has been well established that calcium intake is helpful in the prevention and treatment of osteoporosis, which has become one of the most serious public health problems across the world. However, community-dwelling adults with and without osteoporosis are rarely concerned or even not aware of the potential side effects of high or inappropriate doses of calcium intake. Some recent studies have revealed that excessive calcium intake might increase the risks of cardiovascular diseases. The purpose of this article was to review the health benefits, costs, and consequences of calcium supplementation on osteoporosis/osteoporotic fractures, cardiovascular events, kidney stones, gastrointestinal diseases, and other important diseases. In the end, we suggest that calcium supplementation should be prescribed and taken cautiously, accounting for individual patients’ risks and benefits. Clearly, further studies are needed to examine the health effects of calcium supplementation to make any solid recommendations for people of different genders, ages, and ethnicities. Keywords: calcium, osteoporosis, osteoporotic fractures, cardiovascular diseases, kidney stones, gastrointestinal diseases |
| format |
article |
| author |
Li K Wang XF Li DY Chen YC Zhao LJ Liu XG Guo YF Shen J Lin X Deng J Zhou R Deng HW |
| author_facet |
Li K Wang XF Li DY Chen YC Zhao LJ Liu XG Guo YF Shen J Lin X Deng J Zhou R Deng HW |
| author_sort |
Li K |
| title |
The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health |
| title_short |
The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health |
| title_full |
The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health |
| title_fullStr |
The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health |
| title_full_unstemmed |
The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health |
| title_sort |
good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health |
| publisher |
Dove Medical Press |
| publishDate |
2018 |
| url |
https://doaj.org/article/8e5ba74416814ff7b6375a678dbd2993 |
| work_keys_str_mv |
AT lik thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT wangxf thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT lidy thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT chenyc thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT zhaolj thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT liuxg thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT guoyf thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT shenj thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT linx thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT dengj thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT zhour thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT denghw thegoodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT lik goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT wangxf goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT lidy goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT chenyc goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT zhaolj goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT liuxg goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT guoyf goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT shenj goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT linx goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT dengj goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT zhour goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth AT denghw goodthebadandtheuglyofcalciumsupplementationareviewofcalciumintakeonhumanhealth |
| _version_ |
1718401022059085824 |