Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis

Here, Ratmann et al. show how viral deep sequencing data can be used to reconstruct HIV-1 transmission networks and to infer the direction of transmission in these networks.

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Autores principales: Oliver Ratmann, M. Kate Grabowski, Matthew Hall, Tanya Golubchik, Chris Wymant, Lucie Abeler-Dörner, David Bonsall, Anne Hoppe, Andrew Leigh Brown, Tulio de Oliveira, Astrid Gall, Paul Kellam, Deenan Pillay, Joseph Kagaayi, Godfrey Kigozi, Thomas C. Quinn, Maria J. Wawer, Oliver Laeyendecker, David Serwadda, Ronald H. Gray, Christophe Fraser, PANGEA Consortium and Rakai Health Sciences Program
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/8e75db6f112d4dba8e390f4974b4825a
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spelling oai:doaj.org-article:8e75db6f112d4dba8e390f4974b4825a2021-12-02T16:57:12ZInferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis10.1038/s41467-019-09139-42041-1723https://doaj.org/article/8e75db6f112d4dba8e390f4974b4825a2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09139-4https://doaj.org/toc/2041-1723Here, Ratmann et al. show how viral deep sequencing data can be used to reconstruct HIV-1 transmission networks and to infer the direction of transmission in these networks.Oliver RatmannM. Kate GrabowskiMatthew HallTanya GolubchikChris WymantLucie Abeler-DörnerDavid BonsallAnne HoppeAndrew Leigh BrownTulio de OliveiraAstrid GallPaul KellamDeenan PillayJoseph KagaayiGodfrey KigoziThomas C. QuinnMaria J. WawerOliver LaeyendeckerDavid SerwaddaRonald H. GrayChristophe FraserPANGEA Consortium and Rakai Health Sciences ProgramNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Oliver Ratmann
M. Kate Grabowski
Matthew Hall
Tanya Golubchik
Chris Wymant
Lucie Abeler-Dörner
David Bonsall
Anne Hoppe
Andrew Leigh Brown
Tulio de Oliveira
Astrid Gall
Paul Kellam
Deenan Pillay
Joseph Kagaayi
Godfrey Kigozi
Thomas C. Quinn
Maria J. Wawer
Oliver Laeyendecker
David Serwadda
Ronald H. Gray
Christophe Fraser
PANGEA Consortium and Rakai Health Sciences Program
Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
description Here, Ratmann et al. show how viral deep sequencing data can be used to reconstruct HIV-1 transmission networks and to infer the direction of transmission in these networks.
format article
author Oliver Ratmann
M. Kate Grabowski
Matthew Hall
Tanya Golubchik
Chris Wymant
Lucie Abeler-Dörner
David Bonsall
Anne Hoppe
Andrew Leigh Brown
Tulio de Oliveira
Astrid Gall
Paul Kellam
Deenan Pillay
Joseph Kagaayi
Godfrey Kigozi
Thomas C. Quinn
Maria J. Wawer
Oliver Laeyendecker
David Serwadda
Ronald H. Gray
Christophe Fraser
PANGEA Consortium and Rakai Health Sciences Program
author_facet Oliver Ratmann
M. Kate Grabowski
Matthew Hall
Tanya Golubchik
Chris Wymant
Lucie Abeler-Dörner
David Bonsall
Anne Hoppe
Andrew Leigh Brown
Tulio de Oliveira
Astrid Gall
Paul Kellam
Deenan Pillay
Joseph Kagaayi
Godfrey Kigozi
Thomas C. Quinn
Maria J. Wawer
Oliver Laeyendecker
David Serwadda
Ronald H. Gray
Christophe Fraser
PANGEA Consortium and Rakai Health Sciences Program
author_sort Oliver Ratmann
title Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
title_short Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
title_full Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
title_fullStr Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
title_full_unstemmed Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
title_sort inferring hiv-1 transmission networks and sources of epidemic spread in africa with deep-sequence phylogenetic analysis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/8e75db6f112d4dba8e390f4974b4825a
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