$Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation$
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Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation

Chulaluck Tangmonkongvoragul,1,2 Sumet Supalaset,3 Napaporn Tananuvat,1,2 Somsanguan Ausayakhun1,2 1Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2CMU LASIK Center, Center of Medical Excellence, Faculty of Medicine, Chiang Mai University, Chiang Mai,...

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Autores principales:	Tangmonkongvoragul C, Supalaset S, Tananuvat N, Ausayakhun S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	transepithelial photorefractive keratectomy transprk adolescent two-step prk ex500 Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/8e795f930f7c43ddbb2fb1ae778c4b71
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spelling	oai:doaj.org-article:8e795f930f7c43ddbb2fb1ae778c4b712021-12-02T19:21:04ZTwo-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation1177-5483https://doaj.org/article/8e795f930f7c43ddbb2fb1ae778c4b712021-10-01T00:00:00Zhttps://www.dovepress.com/two-step-transepithelial-photorefractive-keratectomy-with-wavelight-ex-peer-reviewed-fulltext-article-OPTHhttps://doaj.org/toc/1177-5483Chulaluck Tangmonkongvoragul,1,2 Sumet Supalaset,3 Napaporn Tananuvat,1,2 Somsanguan Ausayakhun1,2 1Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2CMU LASIK Center, Center of Medical Excellence, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 3Department of Ophthalmology, Chulabhorn Hospital, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, ThailandCorrespondence: Chulaluck TangmonkongvoragulDepartment of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 Inthawarorot Road, Sri Phum, Muang, Chiang Mai, 50200, ThailandTel +66 53-935512Fax +66 53-936121Email chulaluck.t@cmu.ac.thPurpose: To compare the visual and refractive results obtained after two-step TransPRK using an EX500 excimer laser for low to moderate myopic correction in adolescents and adults.Patients and Methods: Retrospectively, 91 eyes of 52 patients were categorized into four groups based on age and level of myopia. The demographics, data of efficacy, safety, predictability, stability, and post-operative complications were evaluated at 1, 3, 6, and 12 months post-operatively.Results: At 1-month, adolescents with low myopia achieved the highest mean efficacy index (P =0.034). The efficacy indices continuously increased during the 1-year follow-up in all groups, except in adolescents with moderate myopia. The highest safety and efficacy indices were recorded in adolescents with low myopia at 1-year. Post-operative spherical equivalent within ± 0.50 D at 1 year was 48.75% of all treated eyes; however, the final mean refractive spherical equivalent (MRSE) was under-corrected in all groups. By month 3, the percentage of eyes that had grade 0.5 haze was most prevalent in adolescents with moderate myopia (P < 0.001).Conclusion: two-step TransPRK using an EX500 proved to be an effective, predictable, stable and safe procedure for the correction of low to moderate myopia with or without astigmatism at 1 year. Adolescents with low myopia achieved the best-post-operative UDVA, efficacy and safety indices. Adolescents tolerated night visual problems and dry eye symptoms better than adults.Keywords: transepithelial photorefractive keratectomy, TransPRK, adolescent, two-step PRK, EX500Tangmonkongvoragul CSupalaset STananuvat NAusayakhun SDove Medical Pressarticletransepithelial photorefractive keratectomytransprkadolescenttwo-step prkex500OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 4109-4119 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	transepithelial photorefractive keratectomy transprk adolescent two-step prk ex500 Ophthalmology RE1-994
spellingShingle	transepithelial photorefractive keratectomy transprk adolescent two-step prk ex500 Ophthalmology RE1-994 Tangmonkongvoragul C Supalaset S Tananuvat N Ausayakhun S Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation
description	Chulaluck Tangmonkongvoragul,1,2 Sumet Supalaset,3 Napaporn Tananuvat,1,2 Somsanguan Ausayakhun1,2 1Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2CMU LASIK Center, Center of Medical Excellence, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 3Department of Ophthalmology, Chulabhorn Hospital, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, ThailandCorrespondence: Chulaluck TangmonkongvoragulDepartment of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 Inthawarorot Road, Sri Phum, Muang, Chiang Mai, 50200, ThailandTel +66 53-935512Fax +66 53-936121Email chulaluck.t@cmu.ac.thPurpose: To compare the visual and refractive results obtained after two-step TransPRK using an EX500 excimer laser for low to moderate myopic correction in adolescents and adults.Patients and Methods: Retrospectively, 91 eyes of 52 patients were categorized into four groups based on age and level of myopia. The demographics, data of efficacy, safety, predictability, stability, and post-operative complications were evaluated at 1, 3, 6, and 12 months post-operatively.Results: At 1-month, adolescents with low myopia achieved the highest mean efficacy index (P =0.034). The efficacy indices continuously increased during the 1-year follow-up in all groups, except in adolescents with moderate myopia. The highest safety and efficacy indices were recorded in adolescents with low myopia at 1-year. Post-operative spherical equivalent within ± 0.50 D at 1 year was 48.75% of all treated eyes; however, the final mean refractive spherical equivalent (MRSE) was under-corrected in all groups. By month 3, the percentage of eyes that had grade 0.5 haze was most prevalent in adolescents with moderate myopia (P < 0.001).Conclusion: two-step TransPRK using an EX500 proved to be an effective, predictable, stable and safe procedure for the correction of low to moderate myopia with or without astigmatism at 1 year. Adolescents with low myopia achieved the best-post-operative UDVA, efficacy and safety indices. Adolescents tolerated night visual problems and dry eye symptoms better than adults.Keywords: transepithelial photorefractive keratectomy, TransPRK, adolescent, two-step PRK, EX500
format	article
author	Tangmonkongvoragul C Supalaset S Tananuvat N Ausayakhun S
author_facet	Tangmonkongvoragul C Supalaset S Tananuvat N Ausayakhun S
author_sort	Tangmonkongvoragul C
title	Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation
title_short	Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation
title_full	Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation
title_fullStr	Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation
title_full_unstemmed	Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation
title_sort	two-step transepithelial photorefractive keratectomy with wavelight ex500 platform for adolescents and adults with low to moderate myopia: a 12-month comparative evaluation
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/8e795f930f7c43ddbb2fb1ae778c4b71
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Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation

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